keratosis follicularis spinulosa decalvans (kfsd) represents a rare, probably x-linked recessive genodermatosis, characterized by keratosis pilaris of face, trunk and extremities, followed by atrophy, cicatricial alopecia of the scalp, eyebrows and eyelashes, photophobia and corneal abnormalities. we report a rare case of kfsd and review the literature.

This study aims to develop and validate an investigator global assessment score (IGA) for keratosis pilaris (KP), a highly prevalent, benign, follicular disorder, standardize disease assessment. To our knowledge, there is currently no scoring system KP. A composite IGA score, Keratosis Pilaris Area Index (KPAI), was created compared 0-4 defined KP known as KP-IGA. validation done determine the ...

Pityriasis rubra pilaris (PRP) is an uncommon papulosquamous inflammatory dermatosis of unclear aetiology. Its most remarkable clinical findings are palmoplantar hyperkeratosis, orange-red scaling plaques and hyperkeratotic follicular papules. Its extension may vary from localised subtypes to generalised skin involvement with well-demarcated areas of spared skin ("islands of sparing") to erythr...

OBJECTIVE The aim of the study was to assess the prevalence of cutaneous disorders and their relation to disease duration, metabolic control, and microvascular complications in children and adolescents with type 1 diabetes. RESEARCH DESIGN AND METHODS The presence and frequency of skin manifestations were examined and compared in 212 unselected type 1 diabetic patients (aged 2-22 years, diabe...

A quantitative model of the magnetospheric magnetic ®eld is developed using poloidal vector ®elds. This formalism is applied to the ring current region, the distant ®eld and the return currents. The tail model is similar to the unwarped model of Tsyganenko. Several sets of coecients are obtained for di€erent Kp through a ®t of the NSSDC data base. Experimental DB contours and theoretical distr...

To investigate the function of trichohyalin during terminal differentiation of the skin, immunohistochemical studies were performed on trichohyalin and its related proteins, filaggrin and involucrin, the components of the cornified cell envelope. In skin disorders unrelated to tumours, weak trichohyalin expression was found in a few granular cells or in the horny layer of psoriasis, ichthyosis,...

MAPK: mitogen-activated protein kinase MEK: MAPK/ERK kinase INTRODUCTION Several skin lesions resulting from keratinocyte hyperproliferation have been observed in melanoma patients receiving BRAF inhibitor monotherapy. The most common of these lesions are verrucal keratosis, Grover disease, plantar hyperkeratosis, actinic keratosis, cutaneous squamous cell carcinoma, and keratosis pilaris. More...