PURPOSE To investigate whether microRNA (MIR)-184 mutations make a substantial contribution to keratoconus (KCN) among affected Iranian patients. METHODS A total of 47 Iranian KCN patients, diagnosed based on family history, clinical examinations using slit lamp biomicroscopy, refraction and corneal topography were enrolled in this study. The pri-miR-184 encoding gene obtained from the DNAs o...

purpose: to determine the incidence and prevalence of clinical keratoconus (kcn) in yazd province. methods: in this population-based survey, a surveillance program was established in yazd province (population size=990,818). all new clinically diagnosed cases of kcn were registered and referred for topographic imaging during one year (2008-2009) by all local ophthalmologist and optometrists. peo...

Corneal cross-linking (CXL) is an option that in the last decade has demonstrated its efficacy and safety in halting the progression of keratoconus (KCN) and other corneal ectasias. Its indication has been extended beyond the classic definition that required evidence of KCN progression, especially in the presence of some risk factors for a possible progression (particularly the younger age). Ho...

PURPOSE To report a case of unilateral post trabeculectomy globe massage-induced keratoconus (KCN). CASE REPORT A 52-year-old lady with a history of trabeculectomy due to iridocorneal endothelial syndrome in her right eye was instructed to massage her globe to control gradual rise of intraocular pressure 1.5 years after surgery. The patient experienced high astigmatism and marked inferior cor...

PurposeTo introduce the novel parameter of Corneal Contribution to Stress and compare stress distribution patterns between keratoconus normal corneas.DesignProspective, Observational, Cross-sectional StudyParticipantsThe study included 66 eyes 40 subjects diagnosed with (KCN) 155 left from control (NRL) subjects.MethodsTomography was obtained calculate newly proposed (CCS), defined according ho...

The aim of this study was to analyze and compare corneal biomechanics in patients with bilateral keratoconus (KCN) with unilateral Vogt's striae. In this prospective contralateral study, visual acuity, refraction, and corneal biomechanical parameters were evaluated in patients with bilateral KCN with unilateral Vogt's striae using the Ocular Response Analyzer (ORA) (Reichert Inc., Buffalo, NY) ...

purpose: in the present study we have tried to find the most reliable intraocular lens (iol) power calculation formula in patients with keratoconus (kcn) and cataract. methods: in a prospective case series between october 2010 and march 2012, eligible patients with cataract and kcn underwent phacoemulsification with iol implantation. preoperatively, based on iol master keratometric data iol pow...

Purpose To evaluate the magnitudes and axis orientation of anterior corneal astigmatism (ACA) and posterior corneal astigmatism (PCA), the ratio of ACA to PCA, and the correlation between ACA and PCA in the different stages of keratoconus (KCN). Methods This retrospective case series comprised 161 eyes of 161 patients with KCN (104 men, 57 women; mean age, 22.35 ± 6.10 years). The participant...

Keratoconus (KCN) is an ectatic disorder with progressive corneal thinning and a clinical picture of corneal protrusion, progressive irregular astigmatism, corneal fibrosis and visual deterioration. Other ectatic corneal disorders include: post-LASIK ectasia (PLE) and pellucid marginal degeneration (PMD). Corneal crosslinking (CXL) is a procedure whereby riboflavin sensitization with ultraviole...

Purpose To evaluate and compare corneal hysteresis (CH) and corneal resistance factor (CRF) in pellucid marginal degeneration (PMD), keratoconus (KCN), and normal eyes using the Ocular Response Analyzer (ORA). Methods In this retrospective study, corneal biomechanical parameters were measured in patients with PMD (n = 102) and KCN (n = 202) and normal subjects (n = 208) using the ORA. Data, i...