a twelve year old girl, an established case of systemic lupus erythematosus, was referred to us suffering from diplopia and nasal speech for a period of 3 months. neurological examination was conducted which revealed a right-sided sixth nerve palsy and a pulsatile nasopharyngeal mass. neurodiagnostic imaging studies confirmed a giant intracavernous internal carotid aneurysm. the malady of the a...

OBJECTIVE The aim of this study was to assess the IgE serum levels in juvenile systemic lupus erythematosus patients and to evaluate possible associations with clinical and laboratory features, disease activity and tissue damage. METHODS The IgE serum concentrations in 69 consecutive juvenile systemic lupus erythematosus patients were determined by nephelometry. IgG, IgM and IgA concentration...

background: systemic lupus erythematosus is a systemic autoimmune disorder with unclear etiology. the importance of some genes in the development of systemic lupus erythematosus has been implicated. the gene polymorphism in codon 72 has attracted a lot of attention and its role in the occurrence or progression of many cancers and autoimmune diseases especially systemic lupus erythematosus has b...

We present the first reported case of juvenile Systemic Lupus Erythematosus with Klinefelter's syndrome in a 14-year-old Iranian boy who had leg ulcers and arthritis. He had low level of testosterone accompanied with hypergonadotropic hypogonadism. This case emphasizes the importance of two X chromosomes as a risk factor for Systemic Lupus Erythematosus in women and men with Klinefelter's syndr...

central nervous system ranks among the favorite sites to get involved by nocardia astroides. this opportunistic organism complicates many disorders characterized by cellular or humoral immunity disturbances.a 36-year-old woman is being presented, known to have systemic lupus erythematosus (sle) and having received a two year course of corticosteroid treatment. cerebellar abscess was found on di...

Background: Systemic lupus erythematosus is a systemic autoimmune disease that affects almost all organs of the body, and viral infections are involved in its development and progression. The present study aimed to evaluate the serological status of some viral infections in patients with systemic lupus erythematosus and a healthy population. Methods: This descriptive study conducted from May 2...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: to determine the prevalence of cryoglobulins in iranian patients with systemic lupus erythematosus (sle) and evaluate the correlation of cryoglobulins with disease activity in these patients. materials and methods: in a cross-sectional study, we investigated 80 consecutive women who fulfilled the 1982 revised c...

histiocytic necrotizing lymphadenitis or kikuchi's disease is a rare, benign condition of unknown etiology, which is usually characterized by cervical lymphadenopathy and fever. this disease is rarely associated with systemic lupus erythematosus. here we describe, for the first time in iran, a patient who developed systemic lupus erythematosus about 3 years after the initial diagnosis of kikuch...

817 Rev Bras Reumatol 2012;52(6):817-818 In adults with systemic lupus erythematosus (SLE), antinucleosome antibodies have already been described as markers of disease activity and lupus nephritis.1–4 In addition, anti-C1q and antinucleosome antibodies have an amplifying effect on the etiopathogenesis of lupus nephritis in adults.5 In this issue of the Brazilian Journal of Rheumaotlogy, Jesus e...