abstract glaucoma management in pregnant patients is a real challenge, especially when the glaucoma is not controlled with medications. we report the results of 6 incisional glaucoma surgeries for the management of medically uncontrolled glaucoma patients during pregnancy. this retrospective, case series was conducted on the 6 eyes of 3pregnant patients with uncontrolled glaucoma using maximum ...

PURPOSE This study was designed to analyze two candidate genes, myocilin (MYOC) and cytochrome P450 1B1 (CYP1B1), in a Chinese pedigree of juvenile glaucoma with goniodysgenesis. METHODS In a three-generation family of juvenile glaucoma with goniodysgenesis (13 members), six of them were patients with glaucoma and the rest were asymptomatic. All members of the family underwent complete ophtha...

The review is devoted to the genetic nature of congenital glaucoma (CG) and presents clinical forms hereditary single nucleotide polymorphisms identified by genome-wide association studies (GWAS). Glaucoma a genetically heterogeneous disease, patients with same diagnosis often have different molecular causes. role mutations in CYP1B1 gene has been proven pathogenesis hydrophthalmos; MYOC — juve...

Childhood glaucoma poses a diagnostic and therapeutic challenge to ophthalmologists. Difficulty in examination and limitations on ability to perform structural and functional testing of optic nerve make diagnosis and verification of glaucoma control difficult in children. It is well known that an excessive loss of hyperopia is a useful sign in alerting the examining ophthalmologist to the possi...

Superior segmental optic nerve hypoplasia (SSOH) is a congenital anomaly of the optic nerve that is commonly misdiagnosed as normal tension glaucoma (NTG) and/or juvenile open angle glaucoma (JOAG). We demonstrate the utility of SD-OCT in assessing the structure-function correlation when differentiating between SSOH and JOAG.

Uveitis, glaucoma, and cystoid macular edema frequently develop in patients with juvenile idiopathic arthritis. The authors describe a case of cystoid macular edema associated with juvenile idiopathic arthritis that had not responded to intravitreal triamcinolone acetonide and bevacizumab but improved significantly following intravitreal injection with a dexamethasone 0.7 mg implant.

Purpose The purpose of this study was to comparatively evaluate angle dysgenesis in vivo, among congenital, juvenile, and adult-onset open angle glaucoma patients. Methods A cross-sectional evaluation of 96 glaucoma patients, 22 children with primary congenital glaucoma (PCG) old enough to cooperate for optical coherence tomography (OCT), 34 juvenile-onset open angle glaucoma (JOAG) patients,...

S ince Pratap Challa, MD, wrote about genetics and glaucoma for Glaucoma Today in 2003,1 investigators have expanded previously successful research to identify more genes associated with this potentially blinding disease. This article updates the ongoing search for genetic markers for glaucoma and genes that contribute to the disease’s onset and progression, discusses the shift from a singlegen...