Mutations in parkin are implicated in the pathogenesis of autosomal recessive juvenile parkinsonism (AR-JP) disease. We show that homozygote Cys212Tyr parkin mutation in AR-JP patients renders lymphocytes sensitive to dopamine, iron and hydrogen peroxide stimuli. Indeed, dopamine-induced apoptosis by four alternative mechanisms converging on caspase-3 activation and apoptotic morphology: (1) NF...

TO THE EDITOR: Glancy et al. (4) measure the rate of oxygen consumption (Jo) by mitochondria incubated with an ATPconsuming system in the presence of creatine kinase (CK), and they show that this in vitro model of aerobically exercising skeletal muscle conforms to Meyer’s electrical analog of muscle oxidative phosphorylation in vivo (23). I want to suggest that the interpretation of these exper...

2. Dubey JP: 1988, Lesions in sheep inoculated with Sarcocystis tenella sporocysts from canine feces. Vet Parasitol 26:237-252. 3. Dubey JP, Lindsay DS, Speer CA, et al.: 1988, Sarcocystis arieticanis and other Sarcocystis species in sheep in the United States. J Parasitol 74: 1033-1038. 4. Dubey JP, Speer CA, Callis G, Blixt JA: 1982, Development of the sheep-canid cycle of Sarcocystis tenella...

Both laboratory and epidemiological studies published over the past two decades have identified the risk of excess hearing loss when specific chemical contaminants are present along with noise. The objective of this study was to evaluate the potency of JP-8 jet fuel to enhance noise-induced hearing loss (NIHL) using inhalation exposure to fuel and simultaneous exposure to either continuous or i...

1. Manelfe C, Pasquine U, Banks WOo Metrizamide demonstration of the subarachnoid space surrounding the optic nerves. J Comput Assist Tomogr 1978;2: 545-547 2. Haughton VM , Davis JP, Eldevik OP, Gager WE. Optic nerve sheath imaging with metrizamide. lnvest Radio/1978 ;13 :544 3. Haughton VM , Davis JP, Harris GJ, Ho KC. Metrizamide optic nerve sheath opacification. Invest Radiol 1980; 15(4): 3...

The 4 original papers are 1. Larsen AD, Hannerz H, Obel C, Thulstrup AM, Bonde JP, Hougaard KS: Testing the association between psychosocial job strain and adverse birth outcomes design and methods. BMC Public Health 2011, 11: 255. 2. Larsen AD, Hannerz H, Juhl M, Obel C, Thulstrup AM, Bonde JP, Hougaard KS: Psychosocial job strain and risk of adverse birth outcomes: a study within the Danish n...

Abstract: Purpose: This study aims to analyze Knowledge Hiding (KH), Psychological Distress (PD), Stress (PS) on Employees at Mutiara Sukma Mental Hospital NTB. Research Methodology: The sample used was purposive sampling 125 employees of RSJ NTB by distributing online questionnaires. Using the Multiple Linear Regression Analysis method with SPSS version 23 program. Result: results showed that ...

Anisotropic lattice QCD studies of penta-quarks(5Q) with JP = 1/2± and 3/2± are presented at the quenched level together with tetra-quarks(4Q). The standard gauge action at β = 5.75 and O(a) improved quark (clover) action with κ = 0.1410(0.010)0.1440 are employed on the anisotropic lattice with the renormalized anisotropy as/at = 4. The “hybrid boundary condition(HBC)” is adopted to discriminat...

1. Toft G, Hagmar L, Giwercman A, Bonde JP. Epidemiological evidence on reproductive effects of persistent organochlorines in humans. Reprod Toxicol 2004,19:5-26. 2. Toft G, Rignell-Hydbom A, Tyrkiel E, Shvets M, Giwercman A. Quality control workshops in standardization of sperm concentration and motility assessment in multicentre studies. Int J Androl 2005, 28:144-149. 3. Toft G, Axmon A, Giwe...