625 Dynamic changes in synaptic strength are thought to provide a cellular basis for information storage in the nervous system. For example, long-term potentiation (LTP) of synaptic transmission is a long-lasting, activity-dependent form of synaptic plasticity that is expressed by all principal neurons in the hippocampus—a brain structure implicated in certain forms of long-term memory1. In the...

Words do not adequately describe our feelings of sadness and loss with the sudden and totally unexpected passing of Patrick G. Johnston, M.D., the President and Vice Chancellor of Queen’s University Belfast and one of the foremost medical oncologists, cancer center leaders, and educators of his generation. At age 58, “Paddy” was marching onward in his career with the sole aim of bringing his un...