Johnes disease (JD), caused by Mycobacterium avium subsp paratuberculosis (MAP), occurs worldwide as chronic granulomatous enteritis of domestic and wild ruminants. To develop a cost effective vaccine, in a previous study we constructed an attenuated Salmonella strain that expressed a fusion product made up of partial fragments of MAP antigens (Ag85A, Ag85B and SOD) that imparted protection aga...

2 Little is known of the protein expression in Mycobacterium avium subspecies paratuberculosis 3 (MAP) and how this contributes to pathogenesis. In the present study, proteins from both membranes 4 and cytosol were prepared from two strains of MAP; a laboratory-adapted strain K-10 and a recent 5 isolate, strain 187, obtained from a cow exhibiting clinical signs of Johnes disease. SDS-PAGE of 6 ...

2 Little is known of the protein expression in Mycobacterium avium subspecies paratuberculosis 3 (MAP) and how this contributes to pathogenesis. In the present study, proteins from both membranes 4 and cytosol were prepared from two strains of MAP; a laboratory-adapted strain K-10 and a recent 5 isolate, strain 187, obtained from a cow exhibiting clinical signs of Johnes disease. SDS-PAGE of 6 ...

Introduction The basic objectives of this paper are twofold: (1) to show how neural networks might be applied to and used to analyse firms; and (2) to investigate the effect of different 'firm types' on evolutionary processes at the industry level. Applying neural networks to economic, managerial and financial issues is not, in itself, original. In business and finance, neural network analysis ...

Data envelopment analysis (DEA) and multilevel modelling (MLM) are applied to a data set of 54578 graduates from UK universities in 1993 in order to assess the teaching performance of universities. A methodology developed by Thanassoulis & Portela (2002) allows each individual's DEA efficiency score to be decomposed into two components: one attributable to the university at which the student st...

Johne's disease (JD) is a chronic enteric disease caused by Mycobacterium avium subsp. paratuberculosis that affects ruminants. Transmission occurs by the fecal-oral route. A commonly used antemortem diagnostic test for the detection of M. avium subsp. paratuberculosis in feces is liquid culture; however, a major constraint is the 2- to 3-month incubation period needed for this method. Rapid me...

1808 www.thelancet.com Vol 370 December 1, 2007 7 Sakaguchi M, Miyazawa H, Inouye S. Specifi c IgE and IgG to gelatin in children with systemic cutaneous reactions to Japanese encephalitis vaccines. Allergy 2001; 56: 536–39. 8 WHO. Global Advisory Committee on Vaccine Safety, 9–10 June 2005: mouse brain-derived Japanese encephalitis. Wkly Epidemiol Rec 2005; 80: 241–48. 9 Tauber F, Kollaritsch ...