Macrophages undergo apoptosis after infected by Mycobacterium tuber- culosis (M.tb), which is regulated by tumor necrosis factor alpha (TNF-alpha) and has a direct correlation with killing of intracellular bacilli. In order to clarify the role of isoniazid (INH) in the modulation of macrophages apoptosis and intracellular bacilli replication, we performed the following studies using an INH-resi...

A 4-month trial involving 2,563 routine clinical specimens was conducted to compare the improved BACTEC TB system (12B medium) with the conventional Lowenstein-Jensen (LJ) media for the isolation, identification, and susceptibility testing of mycobacteria. One hundred sixty-two mycobacterial isolates were recovered, 147 (91%) with BACTEC and 118 (73%) with LJ media. Of these, 62 were Mycobacter...

In 1941 D.H. Hyers solved the well-known Ulam stability problem for linear mappings. In 1951 D.G. Bourgin was the second author to treat the Ulam problem for additive mappings. In 1982–2005 we established the Hyers–Ulam stability for the Ulam problem of linear and nonlinear mappings. In 1998 S.-M. Jung and in 2002–2005 the authors of this paper investigated the Hyers–Ulam stability of additive ...

Motivated by Chernoff’s bound on asymptotic probability of error we propose the alpha-divergence measure and a surrogate, the alpha-Jensen difference, for indexing and retrieval in image and other databases. The alpha-divergence, also known as Renyi divergence, is a generalization of the Kullback-Liebler divergence and the Hellinger/Battacharya distance between the probability density character...