نتایج جستجو برای: isolated inhibitor model

تعداد نتایج: 2577773  

Journal: :iranian journal of pharmaceutical sciences 0
saeed pirouzpanah faculty of nutrition sciences and food technology, shahid beheshti university of medical sciences and health services, tehran 19395-4741. mohammad r. rashidi drug applied research center, tabriz university of medical sciences, tabriz 51666-14776. abbas delazar drug applied research center, tabriz university of medical sciences, tabriz 51666-14776. seyed vali razavieh faculty of health and nutrition, tabriz university of medical sciences, tabriz 51666-14776. ali asghar hamidi school of pharmacy, tabriz university of medical sciences, tabriz 51666-14776, iran.

flavonoids could serve as potent inhibitors of xanthine oxidase (xo). in the present study, the effects of ruta graveolens l. extract and its major isolated flavonoids, quercetin and rutin, on guinea pig liver xo have been investigated. the inhibitory effects of r. graveolens, quercetin and its glycoside form, rutin, were assayed spectrophotometrically. r. graveolens extract showed moderate inh...

Farzaneh Jokar, Jalal Pourahmad, Mariam Rabiei, Peter J.O Brien,

Introduction: Severe industrial diseases result from the hepatic accumulation of mercury, cadmium or chromium in humans and on the other hand cadmium and dichromate and mercuric salts may induce lung or kidney cancer. Acute or chronic CdCl2, HgCl2 or dichromate administration induces hepatic and nephrotoxicity in rodents. Oxidative stress is often cited as a possible cause of metal induced cell...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شیراز - دانشکده کشاورزی 1393

شوری خاک یکی از عوامل مهم محیطی است که منجر به کاهش عملکرد گیاهان زراعی می شود. شناخت مکانیسم های مقاومت گیاهان در برابر تنش ها می تواند به شناسایی ژن های مقاومت و کاربرد آن ها در اصلاح گیاهان و افزایش محدوده کشت گیاهان منجر شود. روش آنالیز expressed sequence tag (est) و داده های ریزآرایه راهی سریع و منطقی برای شناسایی ژن های نامزد جدید برای مقاومت به تنش ها می باشد. در این تحقیق تعداد 2 کتابخا...

BJ Liu BN Zhang GF Qiao QM Liu YL Hou

Rhododendron dauricum L. is an ancient Chinese traditional herb. The pharmacological effects of R. dauricum extract have been shown in chronic tracheitis. The aim of this study was to investigate the cardiovascular effects of Rhododendron dauricum L. flavonoids (RF) on rats and its mechanisms. This study was performed in isolated vascular rings and a rat model of myocardial infarction and isola...

Journal: :Scientia Plena 2023

Naringin is a flavonoid glycoside found in citrus fruits and grapes with wide range of therapeutic actions. We aimed to study the inotropic effect naringin on rat-isolated atria, dissecting intracellular mechanisms involved this response. Concentration-response curves (0.003-6 mM) were obtained before after pre-incubation selective antagonists. Our results showed that presented biphasic respons...

Mohammad Taghi Goodarzi,

Alpha-1-proteinase inhibitor (API) is one of the acute phase proteins. Following an inflammatory stimuli the concentration of API increased up to four folds. Accompanying these quantitative changes, there is qualitative alterations in the structure of carbohydrate moiety (glycosylation). To determine the alterations in the glycosylation of API in inflammation, API was isolated from the sera of...

Journal: :International Journal of Molecular Sciences 2023

(1) There are several patients with asthma–COPD overlap (ACO). A peptide derived from the primary sequence of a kallikrein inhibitor isolated Bauhinia bauhinioides (pep-BbKI) has potent anti-inflammatory and antioxidant effects. Purpose: To investigate effects pep-BbKI treatment in an ACO model compare them those corticosteroids. (2) BALB/c mice were divided into groups: SAL (saline), OVA (oval...

BJ Liu BN Zhang GF Qiao QM Liu YL Hou

Rhododendron dauricum L. is an ancient Chinese traditional herb. The pharmacological effects of R. dauricum extract have been shown in chronic tracheitis. The aim of this study was to investigate the cardiovascular effects of Rhododendron dauricum L. flavonoids (RF) on rats and its mechanisms. This study was performed in isolated vascular rings and a rat model of myocardial infarction and isola...

Journal: :iranian journal of pharmaceutical sciences 0
ahmad salimi department of pharmacology and toxicology, faculty of pharmacy, shahid beheshti university of medical sciences, tehran, iran. department of pharmacology and toxicology, school of pharmacy, ardabil university of medical science, ardabil, iran. students research committee, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran. melina ramandoost department of pharmacology and toxicology, faculty of pharmacy, shahid beheshti university of medical sciences, tehran, iran jalal pourahmad jaktaji department of pharmacology and toxicology, faculty of pharmacy, shahid beheshti university of medical sciences, tehran, iran

6- mercaptopurine (6-mp) is widely used in clinic as an immunosuppressive for treatment of acute lymphocytic leukemia, crohn's disease, and ulcerative colitis with documented unpredictable hepatotoxicity. the potential molecular cytotoxic mechanisms of 6-mp against isolated rat hepatocytes were searched in this study using “accelerated cytotoxicity mechanism screening (acms)” techniques. t...

Abbas Delazar Ali Asghar Hamidi Mohammad R. Rashidi, Saeed Pirouzpanah Seyed Vali Razavieh

      Flavonoids could serve as potent inhibitors of xanthine oxidase (XO). In the present study, the effects of Ruta graveolens L. extract and its major isolated flavonoids, quercetin and rutin, on guinea pig liver XO have been investigated. The inhibitory effects of R. graveolens, quercetin and its glycoside form, rutin, were assayed spectrophotometrically. R. graveolens...

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