نتایج جستجو برای: ischemiareperfusion injury pyramidal neurons

تعداد نتایج: 484663  

M Hosseini Sharifabad NJ Randel

Animal studies have shown that prenatal stress is able to induce long-lasting neurobiological and behavioral alterations in adult offspring. In spite of the facts that hippocampus is sensitive to early developmental influences and its known functional importance in learning and memory, few data are available on the effect of prenatal stress on the structure of hippocampus. Therefore, this study...

فرخی, فرح, نظیفی, معصومه,

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Journal: :Current Biology 2011

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2004
V E Koliatsos T M Dawson A Kecojevic Yueping Zhou Yi-Feei Wang K-X Huang

Unlike peripheral nervous system neurons and certain groups of nerve cells in the CNS, cortical projection neurons are tolerant of axonal lesions. This resistance is incongruent with the massive death of pyramidal neurons in age-associated neurodegenerative diseases that proceed along corticocortical connections. Some insights have emerged from our previous work showing that pyramidal cells in ...

Journal: :iranian journal of basic medical sciences 0
mohammad hosseini-sharifabad department of biology and anatomical sciences, shahid sadoughi university of medical sciences, yazd, iran abdoreza sabahi department of anatomical sciences, isfahan university of medical sciences, isfahan, iran

objective(s):the hippocampus has been implicated in pathophysiology of schizophrenia. prenatal stress is a contributing risk factor for a wide variety of neuropsychiatric diseases including schizophrenia. this study examined long-term effects of prenatal restraint stress on the stereological parameters in the cornu ammonis (ca) of adult male rats as an animal model of schizophrenia. materials a...

Mohammad Jafar Golalipour, Soraya Ghafari

Objective(s):This study was carried out to evaluate the effect of maternal morphine exposure during gestational and lactation period on pyramidal neurons of hippocampus in 18 and 32 day mice offspring. Materials and Methods: Thirty female mice were randomly allocated into cases and controls. In case group, animals received morphinesulfate 10 mg/kg.body weight intraperitoneally during 7 days bef...

Journal: : 2023

This study aimed to investigate tourniquet-induced compartment syndrome of the limb, consequential development multiple organ dysfunction syndrome, and its counteraction with pentadecapeptide BPC 157 therapy.

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Abstract Background: Stroke is the second leading cause of death in the world and has irreversible consequences. Cerebral ischemia/reperfusion (I/R) through production of oxidants and inflammatory markers causes apoptosis of brain neurons. On the other hand, in various studies, the antioxidant and anti-inflammatory effects of the Malva neglecta have been proven. Therefore, in this study, we inv...

Journal: :physiology and pharmacology 0
abdolrahman sarihi department of physiology, hamadan university of medical sciences, shahid fahmideh avenue, hamadan, iran alireza komaki department of physiology, hamadan university of medical sciences, shahid fahmideh avenue, hamadan, iran tadaharu tsumoto neuronal circuit mechanism research group, riken brain science institute, wako-shi, saitama, japan

introduction: (s)- 3,5-dihydroxyphenylglycine (dhpg) is an agonist for group i metabotropic glutamate receptors. dhpg-induced synaptic depression of excitatory synapses on hippocampal pyramidal neurons is well known model for synaptic plasticity studies. the aim of the present study was to examine the effects of dhpg superfusion on excitatory synapses on pyramidal and fast-spiking gabaergic cel...

ژورنال: Hormozgan Medical Journal 2010
Ahmadpour, SH, Haghir, H, heibanifar, M, Sadeghi, A,

Introduction: The aim of this study was to determine the effects of Insulin and Lascorbic acid on prevention of neuronal in granular layer of dentate gyrus and pyramidal layer of CA3 of hippocampus in streptozotocin-Induced diabetic rats. Methods: In this experimental study, diabetes type 1 was included by a single intraperitoneal injection of streptozotocin (STZ) (60mg/kg) in male adult ...

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