Cutaneous melanocytic lesions, commonly known as moles, are mostly benign; however, some of them are malignant melanomas, the most fatal form of skin cancer. Because the survival rate of melanoma is inversely proportional to the thickness of the tumor, early detection is vital to the treatment process. Many dermatologists have advocated the development of computer-aided diagnosis systems for ea...

The study of graphs and networks accomplished by topological measures plays an applicable task to obtain their hidden topologies. This procedure has been greatly used in cheminformatics, bioinformatics, biomedicine, where estimations based on graph invariants have made available for effectively communicating with the different challenging tasks. Irregularity are mostly characterization nonregul...

One of the important clinical features that differentiates benign melanocytic nevi from malignant melanomas is the irregularity of the lesion border. There are two types of border irregularities: texture irregularities, the small variations along the border, and structure irregularities, the global indentations and protrusions. Texture irregularities are subject to noise, whereas structure irre...

BACKGROUND/PURPOSE The Irregularity Index is a measure of border irregularity from pigmented skin lesion images. The measure attempts to quantify the degree of irregularity of the structural indentations and protrusions along a lesion border. A carefully designed study has shown that the parameters derived from the Irregularity Index were highly correlated with expert dermatologists' notion of ...

The El Niño/Southern Oscillation (ENSO) phenomenon is the dominant climatic fluctuation on interannual time scales. It is an irregular oscillation with a distinctive broadband spectrum. In this article, we discuss recent theories that seek to explain this irregularity. Particular attention is paid to explanations that involve the stochastic forcing of the slow ocean modes by fast atmospheric tr...

BACKGROUND Even if atrial fibrillatory rate (AFR) has been related to clinical outcome in patients with atrial fibrillation (AF), its relation with ventricular response has not been deeply studied. The aim of this study was to investigate the relation between AFR and RR series variability in patients with AF. METHODS Twenty-minute electrocardiograms in orthogonal leads were processed to extra...

This study examined changes in the dental arches that occur in untreated persons between late adolescence and the fifth or sixth decade of life. Longitudinal dental casts from 82 subjects were obtained as part of a recall study of subjects from the University of Michigan Elementary and Secondary School Growth Study. From the parent sample, three groups were identified. The untreated sample comp...

AIMS Reduced irregularity of RR intervals in permanent atrial fibrillation (AF) has been associated with poor outcome. It is not fully understood, however, whether modification of atrioventricular (AV) conduction using rate-control drugs affects RR variability and irregularity measures. We aimed at assessing whether atrial fibrillatory rate (AFR) and variability and irregularity of the ventricu...