Iron deficiency anemia (IDA) is common in many chronic diseases, and intravenous (IV) iron offers a rapid and efficient iron correction. This trial compared the efficacy and safety of iron isomaltoside and iron sucrose in patients with IDA who were intolerant of, or unresponsive to, oral iron. The trial was an open-label, comparative, multi-center trial. Five hundred and eleven patients with ID...

BACKGROUND Intravenous iron is typically administered during the hemodialysis (HD) procedure. HD patients may be prescribed high-flux (HF) or high-efficiency (HE) dialysis membranes. The extent of iron sucrose and iron dextran removal by HD using HF or HE membranes and by ultrafiltration rate (UFR) is unknown. METHODS Two in vitro HD systems were designed and constructed to determine the dial...

In this research, the amount of Iron removal by bioleaching of a kaolin sample with high iron impurity with Aspergillus niger was optimized. In order to study the effect of initial pH, sucrose and spore concentration on iron, oxalic acid and citric acid concentration, more than twenty experiments were performed. The resulted data were utilized to train, validate and test the two layer artificia...

Intravenous iron is widely used to maintain adequate iron stores and prevent iron deficiency anemia in patients with chronic kidney disease, yet concerns remain about its long-term safety with respect to oxidative stress, kidney injury, and accelerated atherosclerosis, which are the subjects of this review. Three parenteral iron formulations are available for use in the United States: Iron dext...

BACKGROUND Intravenous low molecular weight iron dextran and iron sucrose have been used for correction of iron deficiency for many years and have been shown to improve anaemia in chronic kidney disease (CKD). However, there is a paucity of head to head comparisons of these parenteral iron preparations. Such comparative efficacy data would be of particular interest in resource-limited African c...

OBJECTIVE The present study was undertaken to assess the impact of intravenous iron sucrose (Feronia IV) in the treatment of iron deficiency anemia observed in gynecological and obstetrical practice. METHODS Seventy-seven practicing gynecologists and obstetricians throughout India collaborated in the recruitment of 145 women over a period of 1 year, of which 143 were analyzable cases. RESUL...

BACKGROUND/AIMS Intravenous (IV) iron preparations are widely used in the management of anemia in ESRD populations. Recent changes in reimbursement policy have dramatically increased the use of IV iron to lower the use of costly erythropoiesis-stimulating agents. These preparations are frequently administered with insufficient attention to the total body iron stores or presence of inflammation ...

OBJECTIVE To study the transfer of parenteral iron sucrose into maternal milk in the postpartum period. STUDY DESIGN Ten healthy lactating mothers with functional iron deficiency 2-3 days after delivery received 100 mg intravenous iron sucrose and were observed together with a control group (n=5) without iron treatment during four days. Milk samples were taken before the treatment and every d...

BACKGROUND Intravenous iron therapy is a treatment option for iron deficient patients who are intolerant to oral iron or where oral iron is ineffective, but with possible adverse effects. Currently, prospective studies comparing different intravenous iron formulations are needed to determine safety and efficacy of these agents. METHODS We conducted a prospective, double-blind, randomized cont...

Objective: We aimed to improve the hematological parameters in pregnant women with iron deficiency anemia (IDA) with the use of iron sucrose complex. Methods: We used iron sucrose complex intravenously and assessed its effects on hematological parameters in pregnant anemic women Fifty pregnant women with hemoglobin level of 8gm/dl or lower were given calculated dose of iron sucrose complex intr...