OBJECTIVE To examine the impact of antenatal supplementation with multiple micronutrients or iron and folic acid compared with folic acid alone on birth weight, duration of gestation, and maternal haemoglobin concentration in the third trimester. DESIGN Cluster randomised double blind controlled trial. SETTING Two rural counties in north west China. PARTICIPANTS 5828 pregnant women and 46...

OBJECTIVE To examine the effect of supplemental prenatal folic acid, folic acid-iron, folic acid-iron-zinc, and multiple micronutrients on maternal morbidity in rural Nepal. METHODS A cluster-randomized double-masked controlled trial of pregnant women who received daily supplements from early pregnancy through 3 months post partum as per the treatment allocation. Women were interviewed at bir...

Folic acid is frequently given to pregnant women at the same time as intermittent preventive treatment (IPTp) with sulfadoxine/pyrimethamine (SP), but it is not known if it interferes with the anti-malarial activity of SP. To investigate this concern, 1,035 Gambian primigravidae were randomized to receive either folic acid (500-1,500 microg/day) together with oral iron (522) or oral iron alone ...

this study presented a mini review on folic acid deficiency and recommendations for its supplementation in thalassemia intermedia (ti). ti is a clinical condition which lies between thalassemia major and thalassemia minor. although ti patients may not need regular blood transfusion, precise diagnosis and management are critical for the prevention of clinical complications and quality of life im...

UNLABELLED Child eating behaviors play an important role in nutrient intake, ultimately affecting child growth and later outcomes in adulthood. The study assessed the effects of iron-folic acid and zinc supplementation on child temperament and child eating behaviors in rural Nepal. Children (N = 569) aged 4-17 months in Sarlahi district, southern Nepal were randomized to receive daily supplemen...

background: this study aimed to investigate different methods used to provide necessary supplementations for pregnant women and obtain reliable data about the general status of health promotion during pregnancy. methods: this descriptive, cross-sectional study was conducted on 401 pregnant women referring to different women’s hospitals of tabriz, including alzahra, taleghani, 29-bahman, zakariy...

BACKGROUND Iron deficiency during pregnancy is a risk factor for anemia, preterm delivery, and low birth weight. Iron/Folic Acid supplementation with optimal adherence can effectively prevent anemia in pregnancy. However, studies that address this area of adherence are very limited. Therefore, the current study was conducted to assess the adherence and to identify factors associated with a numb...

Obstetricians then embarked on a series of research studies to combat anaemia in pregnancy. During 1970s they showed that (i) daily oral iron folate therapy (60 mg of elemental iron and 500 μg of folic acid) prevented fall in haemoglobin (Hb) levels seen in pregnancy and resulted in some improvement in birth weight, and (ii) daily administration of two or maximum tolerated dose of oral iron fol...

OBJECTIVE To assess whether iron and folic acid supplementation reduce the risk of low birthweight (LBW) in women without anaemia. DESIGN Case-control study. SETTING University Hospital of Cantabria. STUDY POPULATION Cases were 322 mothers without anaemia delivering a singleton infant of less than 2500 g. Controls were 934 mothers without anaemia delivering a term non-small-for-gestationa...

Sum mary Aim: To evaluate malnutrition, anemia and related deficiency of vitamin B12, iron and folic acid in children with neurological disease and related nutritional problems. Material and Method: In this study, our aim was to investigate anemia and possible reasons such as iron deficiency, folic acid deficiency and vitamin B12 deficiency among patients with nutritional problems who were admi...