ionizing radiation causes dna damage and chromosome abbreviations on normal cells. the radioprotective effect of celecoxib (clx) was investigated against genotoxicity induced by ionizing radiation in cultured human blood lymphocytes. peripheral blood samples were collected from human volunteers and were incubated at different concentrations at 1, 5, 10 and 50 μm of clx for two hours. at each do...

conclusions the effects of rp knowledge, attitude, and practice on job stress were significant. in order to reduce job stress in radiation environments, ongoing training programs related to self-care and protection principles are recommended. results the prevalence rate of job stress was 22.5% based on calculation formulas and possible scores on the jcq. sex, rp-knowledge, attitude, practice, a...

BACKGROUND Hesperidin is a flavonoid with antioxidant, anti-inflammatory, and immune modulatory activities. Photoaging is a consequence of chronic exposure to the sun and ultraviolet (UV) radiation. This study was designed to evaluate the efficacy of hesperidin against photoaging of dorsal skin in hairless mice. METHODS Hairless male mice (6-week-old) were divided into three groups (n = 7): c...

the currently reactor wreckage in fukushima raised the following important questions: is our knowledge of the possible dangers of ionizing radiation sufficient to warrant special action? what is the role of the medical community in technical radiation accidents from windscale to fukushima? what is the role of the medical community in terrorist radiation attacks? are we prepared for those challe...

the aim of this study was to investigate the radioprotective effect of thymol as a natural product against salivary glands dysfunction induced by ionizing radiation in rats. the rats were treated with thymol at dose of 50 mg/kg before exposure to radiation at dose 15gy. salivary gland function was evaluated with radioisotope scintigraphy and then salivary gland to background counts ratio was ca...

A bystander effect is biological changes in non-irradiated cells by transmitted signals from irradiated bystander cells, which causes the radiation toxic effects on the adjacent non-irradiated tissues. This phenomenon occurs by agents such as ionizing radiation, ultraviolet radiation (UVR) and chemotherapy. The bystander effect includes biological processes such as damage to DNA, cell death, ch...

Introduction: Today ionizing radiation (IR) plays an important role in medicine, both in diagnostic and therapeutic field. Doctors, medical staff and patients are all in danger of side effects of IR so there is a need to protect them against deleterious effects of ionizing radiation.  Thymus vulgaris has biological activities like antioxidant and antibacterial activity. Aim of...

The aim of this study was to investigate the radioprotective effect of thymol as a natural product against salivary glands dysfunction induced by ionizing radiation in rats. The rats were treated with thymol at dose of 50 mg/Kg before exposure to radiation at dose 15Gy. Salivary gland function was evaluated with radioisotope scintigraphy and then salivary gland to background counts ratio was ca...

INTRODUCTION Hesperidin (HES), as the most abundant flavonoid existing in the citrus, is widely used by human daily. The radio-protective effects of Hesperidin have been confirmed in various measurement systems. This study aimed to evaluate the effects of Hesperidin on the changes in the apoptosis level and expression of apoptotic genes target (bax, bcl-2 and ration of bax/bcl-2) in the periphe...

  Ionizing radiation has long been known to produce detrimental biological effects. Although these harmful effects are the results of high doses of exposure, some other maladies such as mutation and cancer seems  to be induced at low doses of exposure. In recent decades, however, some pioneer scientists have indicated that ionizing radiation like many other essential agents has toxic effects  ...