Recent confirmation of intrinsic bacterial contamination of 10% povidone-iodine solution has raised questions regarding the bactericidal mechanism of iodophors and the possibility for survival of vegetative bacterial cells in iodophor solutions. In this laboratory investigation, five different species were exposed to various dilutions of three commercial preparations of 10% povidone-iodine solu...

background: to determine the efficacy of three different antiseptic solutions (control group (i), antibiotic solution – neomycin and polymyxin (ii), chlorhexidine 0.4% (iii), and povidone – iodine 10% (iv)) in disinfecting contaminated bone fragments. methods: under sterile conditions, the femora of 12 rabbits were removed and cut into six millimeter pieces. a total of 200 bone specimens were o...

in order to determine the effects of intraocular 0.05% povidone-iodine preparation in the prevention of bacterial endophthalmitis in a rabbit model, 28 albino rabbits were randomly assigned to 4 equal groups. a concentration of 5x 108 organisms (0.03 ml) in logarithmic growth phase of s. epidermidis, s. aureus, proteus mirabilis and pseudomonas aeruginosa, were injected separately in the anteri...

Skin antisepsis prior to the induction of spinal anesthesia is essential because of the potential for infectious complications. Povidone-iodine is a widely used antiseptic solution for skin preparation before spinal anesthesia, and chlorhexidine alcohol solution is a commonly used alternative to povidone-iodine. Previous studies have shown that chlorhexidine is more effective than povidone-iodi...

hydrogen peroxide is an important mild oxidant which is widely used in various applications including remediation of waste waters and drinking water resources. the safe level of h2o2 residue has to be controlled through accurate and precise measurement methods. a facile spectrophotometric method for the determination of hydrogen peroxide is based on the reaction of iodine solution with toluidin...

We studied the kinetics of iodine in various forms, in order to establish appropriate guidelines of iodine prophylaxis for thyroid blockade at nuclear emergency in "iodine rich areas", such as Japan. First, the effect of equivalent dose of potassium iodide (KI) (solution vs. tablet) was evaluated with excretions of urinary iodine (UI) at Nagasaki, Japan, and it was revealed that there was no di...

In the presence of iodine at pH 5.0-6.0 a solution of pepsin absorbs iodine and the specific proteolytic activity of the solution decreases. The activity is less than 1 per cent of the original activity when the number of iodine atoms per mol of pepsin is 35-40. If the pH is 4.5 or less, iodine reacts very slowly and there is a correspondingly slower loss in activity. Glycyl tyrosine reacts wit...

OBJECTIVE To determine the efficacy of 2.5% and 1.25% Povidone-Iodine solution for Ophthalmia neonatorum prophylaxis. STUDY DESIGN Interventional study. PLACE AND DURATION OF STUDY Eye Department, Combined Military Hospital, Sargodha, from May to November 2014. METHODOLOGY Atotal of 200 eyes of 100 newborn babies were enrolled and divided into two groups of 100 right eyes and 100 left eye...

A new method for patterning surfaces with organic structures, termed "dip-pen" nanolithography (DPN), has been developed. DPN allows one to deliver collections of molecules to a surface in a positive printing mode. The technique offers 15 nm linewidths and 5 nm spatial resolution. Current capabilities and future applications of DPN are discussed.

In order to determine the effects of intraocular 0.05% povidone-iodine preparation in the prevention of bacterial endophthalmitis in a rabbit model, 28 albino rabbits were randomly assigned to 4 equal groups. A concentration of 5x 108 organisms (0.03 mL) in logarithmic growth phase of S. epidermidis, S. aureus, Proteus mirabilis and Pseudomonas aeruginosa, were injected separately in the a...