The peptides alpha-melanocyte-stimulating hormone (alpha-MSH) and oxytocin have very similar effects on several behaviours, including male sexual behaviour. Both induce penile erection and enhance copulatory behaviour when given centrally, suggesting that their central actions are not independent. Here, we used intromission as a physiological stimulus to investigate whether some central effects...

Objective. We studied prosexual effects of Eremomastax speciosa aqueous extract in male adult rats. Materials and Methods. 100 and 500 mg/kg of extract were administered orally (days 0, 1, 4, 7, 14, and 28 (posttreatment)). The sexual behavior of rats receiving a single dose (500 mg/kg) was also evaluated after pretreatment with Lω-NAME (10 mg/kg), haloperidol (1 mg/kg), or atropine (5 mg/kg). ...

Antidepressants, including tricyclics, monoamine oxidase inhibitors and selective serotonin reuptake inhibitors cause sexual dysfunctions such as decreased sexual desire, erectile difficulties, and delayed ejaculation. Studies have shown that treatment with fluoxetine inhibits several components of sexual behavior in male rats. It is known that sexual experience improves the sexual behavior of ...

Systemically-administered dopaminergic drugs have been found to facilitate sexual behavior of men and male rats. The present experiments investigated the localization within the brain of dopaminergic effects on copulation of male rats. Apomorphine, a dopamine agonist, was microinfused into the medial preoptic area, caudate-putamen, nucleus accumbens, lateral septum and lateral ventricle. The lo...

AIM To study the effects of Boesenbergia rotunda (Krachai) on sexual behaviour in male albino rats. METHODS Thirty-two male Wistar rats were equally divided into four groups: experimental groups were gavaged with the ethanolic extract of the rhizome of B. rotunda at doses of 60, 120 and 240 mg/kg and a control group received distilled water, for 60 days. Sexual behaviour, reproductive organs,...

Aim: To evaluate the phytochemical constituents and the aphrodisiac potential of the aqueous extract of Fadogia agrestis (Rubiaceae) stem in male albino rats. Methods: The aqueous stem extract of the plant was screened for phytochemical constituents. Male rats were orally dosed with 18 mg/kg, 50 mg/kg and 100 mg/kg body weight, respectively, of the extract at 24 h intervals and their sexual beh...

The leaves of Ocimum gratissimum Linn. (Labiatae) have been used in Ayurvedic medicine since ancient times for the treatment of male sexual disorders. The present study investigated the effect ethanolic extract of ram tulsi on general mating behaviour, libido, potency along with its likely gastric ulceration and adverse effects on sexually normal male albino mice. The suspension of the extract ...

AIM To evaluate the phytochemical constituents and the aphrodisiac potential of the aqueous extract of Fadogia agrestis (Rubiaceae) stem in male albino rats. METHODS The aqueous stem extract of the plant was screened for phytochemical constituents. Male rats were orally dosed with 18 mg/kg, 50 mg/kg and 100 mg/kg body weight, respectively, of the extract at 24 h intervals and their sexual beh...

BACKGROUND Aloe barbadensis (AB) is a short stemmed succulent medicinal herb that is being used by locals in Nigeria to enhance libido. Therefore this study evaluates the aphrodisiac potential and acute toxicological effect of A. barbadensis (AB) root in male Wistar rats. METHODS Aphrodisiac potential was determined following the oral administration of graded doses (100, 200 and 400 mg/kg) of...

The aim of this study was to investigate the effects of Ginkgo biloba extract (EGb 761) on male copulatory behavior in rats. EGb 761 (1 mg/ml) induced significant production of testosterone (T) in rat Leydig cells in vitro. Its effects on sexual behavior were then tested in Long-Evans male rats after 7, 14, 21, or 28 days of oral gavage of vehicle (distilled water) or EGb 761 at doses of 10, 50...