Virtual stain transfer is a promising area of research in Computational Pathology, which has great potential to alleviate important limitations when applying deep-learning-based solutions such as lack annotations and sensitivity domain shift. However, the literature, majority virtual staining approaches are trained for specific or combination, their extension unseen stainings requires acquisiti...

Lens major intrinsic protein (MIP) is the founding member of the MIP family of membrane channel proteins. Its isolation from ovine lens fibre cell membranes and its two-dimensional crystallization are described. Membranes were solubilized with N-octyl-beta-D-glucoside and proteins fractionated by sucrose gradient centrifugation containing decyl-beta-D-maltoside. MIP was purified by cation excha...

That similar words can prime one another isn’t news. However, recently this phenomenon has been exploited to make inferences about conceptual representations. What types of similarity matter? While there is evidence that similarity in function, shape, and even manipulation figure in the organization of semantic memory, evidence for color similarity is sparse. This is surprising: intuition sugge...

The Mixed Stain Study 3 (MSS3) interlaboratory challenge exercise evaluated the 2001 performance of STR multiplex DNA typing systems using a set of seven DNA extracts of designed concentration and composition. This initial report focuses on the linkages connecting the measurement of the concentration of DNA ([DNA]) to the observed STR multiplex signal intensities. There is a causal relationship...

BACKGROUND Aggregation of insulin into insoluble fibrils (fibrillation) may lead to complications for diabetes patients such as reduced insulin potency, occlusion of insulin delivery devices, or potentially increased immunological potential. Even after extensive investigation of fibril formation in regular human insulin, there are little published data about the intrinsic fibrillation of fast-a...