La cuarta revolución industrial trajo consigo la integración de diversas habilidades permeables, mismas que, orientadas a estudiantes perfiles ingeniería, mantienen una visión integral que permite ofertar educación interdisciplinaria. Gracias lo anterior, asignaturas como Mecatrónica puedan diseñar, elaborar y adaptar prótesis para pacientes amputados dentro su formación científica social, ampl...

TriN 2755 is an alkylating antineoplastic agent for intravenous (IV) use, carrying the triazene group as the cytotoxic principal. Using a standard 3 + 3 design, a phase I study was performed in tumour bearing dogs to determine the maximum tolerated dose (MTD), the dose limiting toxicity (DLT), and pharmacokinetic (PK) profile of TriN 2755. Thirty dogs were included in the study. TriN 2755 was a...

Remote Procedure Calls (RPC) are widely used over the Internet as they provide a simple and elegant way of interaction between the client and the server. This paper proposes a solution for securing the remote procedure calls (RPC) by tunneling it through HTTPS (Hypertext Transfer Protocol over Secure Socket Layer). RPC over HTTP actually uses the Secure Socket Layer (SSL) protocol as a transpor...

As HTTPS deployment grows, middlebox and antivirus products are increasingly intercepting TLS connections to retain visibility into network traffic. In this work, we present a comprehensive study on the prevalence and impact of HTTPS interception. First, we show that web servers can detect interception by identifying a mismatch between the HTTP User-Agent header and TLS client behavior. We char...

In this paper, the authentication system of the HTTPS protocol is considered from an economical perspective. The use of SSL certificates to authenticate web servers has a number of known technical flaws but is widely used. The different actors of the HTTPS authentication system are identified and the study of their roles and incentives for security shows the lack of a clear reason to progress t...

HTTPS ensures that the Web has a base level of privacy and integrity. Security engineers, researchers, and browser vendors have long worked to spread HTTPS to as much of the Web as possible via outreach efforts, developer tools, and browser changes. How much progress have we made toward this goal of widespread HTTPS adoption? We gather metrics to benchmark the status and progress of HTTPS adopt...

The use of secure connections using HTTPS as the default means, or even the only means, to connect to web servers is increasing. It is being pushed from both sides: from the bottom up by client distributions and plugins, and from the top down by organisations such as Google. However, there are potential technical hurdles that might lock some clients out of the modern web. This paper seeks to me...

Protecting communication content at scale is a difficult task, and TLS is the protocol most commonly used to do so. However, it has been shown that deploying it in a truly secure fashion is challenging for a large fraction of online service operators. While Let’s Encrypt was specifically built and launched to promote the adoption of HTTPS, this paper aims to understand the reasons for why it ha...