In nine patients with severe intracranial disease causing increased intracranial pressure (ICP), the effects on ICP and cerebral perfusion pressure (CPP) of the following manoeuvres were studied: (1) endotracheal intubation, (2) addition of 50% nitrous oxide to the inspired gas after hyperventilation with oxygen and thereafter (3) addition of halothane to the nitrous oxide/oxygen mixture. The m...

BACKGROUND Hyperthermia is a common secondary insult in traumatic brain injury (TBI). The aim was to evaluate the relationship between hyperthermia and intracranial pressure (ICP), and if intracranial compliance and cerebral blood flow (CBF) pressure autoregulation affected that relationship. The relationships between hyperthermia and cerebral oximetry (BtipO2) and cerebral metabolism were also...

retrospective and prospective studies looking at the role of cerebrospinal fluid pressure (csfp)/intracranial pressure (icp) have stimulated new theories and hypotheses regarding the underlying causal events for glaucoma. most recently, studies supporting a low csfp/icp as a risk factor for glaucoma have been published. this review summarizes the current understanding of csfp/icp and its potent...

BACKGROUND The increased intracranial pressure can significantly complicate the perioperative period in major abdominal surgery, increasing the risk of complications, the length of recovery from the surgery, worsening the outcome. Epidural anesthesia has become a routine component of abdominal surgery, but its use in patients with increased intracranial pressure remains controversial. The goal ...

Sudden increases in intracranial pressure (ICP) are extremely serious and can be life-threatening. Up to the present moment, effective methods have been studied to return the ICP to normal levels after a rapid increase has occurred. This study analyzes different characteristics of the ICP signal just prior to the occurrence of an increase, and compares it with the characteristics of the signal ...

Intracranial pressure and intracranial compliance When it is monitored, the ICP tracing is a ballistic waveform similar to the systemic arterial pressure curve (Fig. 1); it has a narrow “pulse pressure” and is expressed, by convention, as its mean measured in millimeter of mercury (mmHg). The normal mean ICP is generally between 5-10 mmHg, and it fluctuates to higher levels depending on physiol...

Pathophysinlogy of increased intraeranial pressure 1 The intracranial pressure ([CP) may be defined as the fluid pressure in the ventricular and lumbar subarachnoid space in a supine subject, with reference to atmospheric pressure. In normal individuals this pressure may be as high as 10mmHg. The static ICP is a reflection of the factors involved in cerehrospinal fluid (CSF) dynamics. 2 Cerebro...

The basic concept of Intracranial Pressure and its elivation in pathological conditions is discussed. The e&ects of Barbiturates, Corticosteroids, Furosamide, man-nitol, urea hyperventilation and hypothermia are mentioned. Experimental data from the published literature are reported. The brain, by virtue of the fact that it is encased in a container with rigid walls, is unique among the organs ...

Since Monro published his observations on the nature of the contents of the intracranial space in 1783, there has been investigation of the unique relationship between the contents of the skull and the intracranial pressure (ICP). This is particularly true following traumatic brain injury (TBI), where it is clear that elevated ICP due to the underlying pathological processes is associated with ...