AIM To investigate the effect of concentrated growth factors (CGFs) in human intrabony defect treatment. METHODS Thirty-one intrabony defects were randomly treated with CGFs + bovine porous bone mineral (BPBM) or BPBM alone. Probing depth, clinical attachment level and hard tissue fill were evaluated at baseline and 1 year post surgery. RESULTS No differences in any of the investigated para...

BACKGROUND Combination of platelet-rich fibrin (PRF) and bone substitutes for the treatment of intrabony pockets is based on sound biologic rationale. The present study aimed to explore the clinical and radiographic effectiveness of autologous PRF and calcium phosphosilicate (CPS) putty alone and in combination in treatment of intrabony defects. MATERIALS AND METHODS A total of 45 intrabony d...

objectives:  the efficacy of adding platelet-rich plasma (prp) to demineralized freeze-dried bone allograft (dfdba) in order to improve the clinical and radiographic results obtained in treatment of deep periodontal intrabony defects has yet to be fully elucidated. materials ­and methods: this double blind, split-mouth randomized controlled clinical trial was conducted on 12 patients with two c...

OBJECTIVES The efficacy of adding platelet-rich plasma (PRP) to demineralized freeze-dried bone allograft (DFDBA) in order to improve the clinical and radiographic results obtained in treatment of deep periodontal intrabony defects has yet to be fully elucidated. MATERIALS AND METHODS This double blind, split-mouth randomized controlled clinical trial was conducted on 12 patients with two com...

background and aims. connective tissue grafts with and without periosteum is used in regenerative treatments of bone and has demonstrated successful outcomes in previous investigations. the aim of present study was to evaluate the effectiveness of connective tissue graft with and without periosteum in regeneration of intrabony defects. materials and methods. in this single-blind randomized spli...

BACKGROUND Studies investigating the use of platelet-rich plasma (PRP) in the treatment of intrabony defects have yielded mixed results. The aim of our study was to evaluate the efficacy of PRP by comparing clinical attachment level (CAL) and pocket depth (PD) for patients who received PRP as an adjunct to periodontal intrabony defect therapy with those for patients who did not. We also analyze...

OBJECTIVES The aim of the present study was to evaluate the efficacy of autogenous bone graft (ABG) and nano-crystalline hydroxyapatite (Ostim) in the management of human intrabony periodontal defects. STUDY DESIGN Twenty-four similar two and three wall intrabony periodontal defects with ≥5 mm probing depths and ≥3 mm depths of intrabony component in 12 healthy patients were selected. One def...

introduction: bone regeneration grafts (brg) are widely used in the treatment of osseous defects and oral surgery. the various techniques and associated success rates of bone augmentation require evaluation by systematic review and meta-analysis of eligible studies. the aim of this systematic review was to compare alveolar bone regeneration in humans using bio-oss and autogenous bone graft. mat...

Background and aims. Connective tissue grafts with and without periosteum is used in regenerative treatments of bone and has demonstrated successful outcomes in previous investigations. The aim of present study was to evaluate the effectiveness of connective tissue graft with and without periosteum in regeneration of intrabony defects. Materials and methods. In this single-blind randomized spli...