Background: Studies have shown that abdominal adhesions occur due to an oxidative stress by ROS. Sargassum sp. extract contains many antioxidative compounds that might be utilized to interrupt this process. This study intends to study the efficacy of Sargassum sp. extract on preventing abdominal adhesions. Methods: In this study, 20 female rats were divided into two groups. Group 1 receive Sarg...

The use of a bioresorbable, hyaluronate membrane during exploratory celiotomy in horses minimizes postoperative intra-abdominal adhesion formation. In horses at an increased risk of intra-abdominal adhesion formation, the application of hyaluronate membranes during exploratory celiotomy may reduce the morbidity and mortality associated with abdominal surgery. Authors’ address: Depts. of Patholo...

BACKGROUND Intra-abdominal adhesions are a very common complication following abdominal surgery. Our previous studies have demonstrated that the inhibition of inflammation at the sites of peritoneal injury can prevent the formation of intra-abdominal adhesions. Resveratrol is a natural extract with a broad range of anti-inflammatory effects. Therefore, we propose that resveratrol can reduce the...

Postoperative intra-abdominal adhesion is a very common complication after abdominal surgery. One clinical problem that remains to be solved is to identify an ideal strategy to prevent abdominal adhesions. Keratinocyte growth factor (KGF) has been proven to improve the proliferation of mesothelial cells, which may enhance fibrinolytic activity to suppress postoperative adhesions. This study inv...

BACKGROUND Postoperative intra-abdominal adhesion is associated with high morbidity and mortality. Smad7, a protein that occupies a strategic position in fibrogenesis, inhibits the transforming growth factor (TGF) beta/Smad signalling pathway. In this study the therapeutic potential of exogenous Smad7 in preventing fibrogenesis in postoperative intra-abdominal adhesion was investigated. METHO...

Peritoneal adhesions are challenging in abdominal surgery. In spite of different kinds of treatments still no definitive and effective treatment is suggested. To determine the prevention effects of intraperitoneal (ip) methylene blue in post surgical adhesion formation 44 rabbits were randomly divided in two groups of equal number. Group I received an intra peritoneal injection of a 1% suspensi...

  Occurrence of adhesions after pelvic and abdominal surgery is a well known problem. Previous surgical procedures are by far the most common cause of intra abdominal a adhesion. In over  10℅ of infertile women, adhesion formation is the main cause of their problem. Moreover postoperative adhesions are the most common cause of intestinal obstruction in the Western world. Although the cause of ...

HYPOTHESIS The use of certain surgical adhesion reduction devices where there is a risk of concomitant bacterial contamination potentiates intra-abdominal infection. DESIGN Evaluation of adhesion reduction devices in an experimental model of intra-abdominal infection. SETTING Experimental animal model. INTERVENTIONS Adhesion reduction devices were administered at the time of bacterial cha...