BACKGROUND A mechanical intestinal obstruction (MIO) can generate intraabdominal hypertension (IAH) that is life threatening. The intestines are very sensitive to IAH since the low splanchnic perfusion causes intestinal hypoxia, local acidosis and bacterial translocations. This may lead to acute intestinal distress syndrome (AIDS). The identification of intestinal injuries during IAH and its co...

Objective- This study examined the effect of Crataegus hydroalcoholic extract (CHE) on intestinal ischemia-reperfusion (I/R) in rats. Design- Experimental study Animals- 25 adult male Wistar rats Procedures- Rats weighing 200±25 g were randomly divided into five individual groups as follows: sham group without...

BACKGROUND Assessment of intestinal activity and severity of Crohn's disease (CD) is crucial to guide treatment. In this study, we aimed to investigate the accuracy of spectral computed tomography (CT) in this assessment and make a comparison with conventional CT. METHODS A total of 50 patients with ileocolonic CD underwent spectral CT scanning. Conventional CT and spectral CT images were rec...

background many studies have reported an association between periodontal infections and some systemic diseases such as respiratory and cardiovascular diseases. some studies found a direct association between chronic gastritis caused by helicobacter pylori (hp) infection and poor periodontal health. methods in a cross-sectional study from november 2014 to december 2015 in kerman, the largest pro...

Antisecretory drugs such as histamine H2-receptor antagonists (H2-RAs) and proton pump inhibitors (PPIs) are commonly used for the treatment of gastric and duodenal ulcers induced by nonsteroidal anti-inflammatory drugs (NSAIDs). However, the effects of these drugs on NSAID-induced small intestinal ulcers are not fully understood. The effects of H2-RAs and PPIs on NSAID-induced gastrointestinal...

BACKGROUND The pathogenesis of non-steroidal anti-inflammatory drug (NSAID) enteropathy is complex. It involves uncoupling of mitochondrial oxidative phosphorylation which alters the intercellular junction and increases intestinal permeability with consequent intestinal damage. Metronidazole diminishes the inflammation induced by indomethacin but the mechanisms remain speculative. A direct effe...

Background: Gastric disorders are responsible for a great deal of mortality and morbidity one the most common encountered problems in clinical practice. H. Pylori infection is majority acid peptic disease also known carcinogen. Intestinal metaplasia considered precancerous lesion. We studied incidence pylori mucin histochemistry different gastric lesions.
 Methods: This study was conducted...