نتایج جستجو برای: interleukin 33

تعداد نتایج: 221536  

2017
Mehwish Younas Christina Psomas Vikram Mehraj Renaud Cezar Pierre Portales Edouard Tuaillon Adeline Guigues Jacques Reynes Pierre Corbeau Jean-Pierre Routy

INTRODUCTION Interleukin-33 (IL-33) is a cell damage-induced alarmin. The plasma concentration of suppression of tumorogenicity (sST2), a surrogate marker of IL-33 production, is a prognostic marker of cardiovascular disease. OBSERVATION Recently, we reported that sST2 plasma levels were elevated in early HIV-1 infection and linked to markers of microbial translocation and of T cell activatio...

Journal: :Cytokine 2016
Tania Gajardo Francisco Pérez Claudia Terraza Mauricio Campos-Mora Randolph J Noelle Karina Pino-Lagos

Several molecules have been described as CD4+ T cells differentiation modulators and among them retinoic acid (RA) and more recently, IL-33, have been studied. Due to the similarities in T helper cell skewing properties between RA and IL-33, we asked whether IL-33 intersects, directly or indirectly, the RA signaling pathway. Total CD4+ T cells from DR5-luciferase mice were activated in the pres...

2017
Lei Tu Jie Chen Dandan Xu Zhongming Xie Bing Yu Ying Tao Guixiu Shi Lihua Duan

Accumulated data have shown that alternatively activated macrophage exerts a modulatory role in many diseases, including colitis. Interleukin-33 (IL-33), a critical modulator in adaptive and innate immune, has been implicated in autoimmunity and inflammation. Previously, we have reported that IL-33 functions as a protective modulator in TNBS-induced colitis, which is closely related to a Th1-to...

2014
Vuvi G. Tran Hong R. Cho Byungsuk Kwon

IL-33 is a member of the IL-1 cytokine family and plays a role in the host defense against bacteria, viruses, and fungi. In this study, we investigated the function of IL-33 and its receptor in in vitro macrophage responses to Candida albicans. Our results demonstrate that pre-sensitization of isolated peritoneal macrophages with IL-33 enhanced their pro-inflammatory cytokine production and pha...

Journal: :Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016
Xiaoyan Ren Mingzhen Guo Caili Liu Tao Huang Qiang Li Mengmeng Han Weiqing Song Xiuming Tang Shiguo Liu

BACKGROUND/AIMS Preeclampsia (PE) is a systemic inflammatory response syndrome involving varieties of cytokines, and previous studies have shown that IL-33 and its receptor IL-1RL1 play pivotal roles in the development of it. As a polygenetic hereditary disease, it is necessary to study the gene analysis for PE. Therefore, the present study was to determine whether IL-33 rs3939286 and IL-1RL1 r...

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