drug therapy is a complex and important process and because of the importance of drug interactions, especially in in-patients, accompanying problems and obstacles would exist as a result of concomitant use of drugs in these patients. for this purpose 3130 prescription order forms from bou-ali hospital were collected and all potential drug interactions presentwere extracted and evaluated in term...

multi-environment trials play a significant role in selecting the best cultivars to be used at different locations. the objective of this study was to identify grain and forage yields stability of grass pea advanced lines across different locations. the 14 advanced lines of grass pea, developed by the international center for agricultural research in dry areas (icarda), were tested at three dif...

background: communication is very important in human societies in connection with the exchange of ideas and information between the instructor and student. the current research aimed to study factors that influence the interaction between the instructor and student from the perspective of shushtar medical sciences students. methods: this descriptive - cross sectional study was conducted in ahva...

the binding data for interaction of a homologous series of n-alkyl sulfates with alkyl chainlengths from c8 to c12 with insulin were analyzed on basis of hill equation for two classes ofbinding sites .the intrinsic gibbs free energies were calculated and resolute on basis ofelectrostatic and hydrophobic contributions the estimation of these contributions reveals themajor role of electrostatic i...

abstractintroduction: cancer is caused by genetic abnormalities, such as mutation of ontogenesis or tumor suppressor genes which alter downstream signaling pathways and protein-protein interactions. comparison of protein interactions in cancerous and normal cells can be of help in mechanisms of disease diagnoses and treatments. methods: we constructed protein interaction networks of cancerous a...

background: clopidogrel is a prodrug that converts in the liver to an active thiol metabolite, which irreversibly inhibits the platelet p2y12 adenosine diphosphate receptor. it seems that methadone as cyp2c19 inhibitor affects ticlopidine activity in vivo. this study aimed to test the ability of methadone in changing ticlopidine pharmacokinetics. methods: we conducted a case–control study in 10...

background some herbal anticancer agents have direct interactions with dna. objectives the present study aimed to investigate the interaction of ctdna with rosemary flowers. materials and methods we used uv-vis, fluorescence and circular dichroism (cd) spectroscopic techniques. results the absorption of dna at 260 nm increased on addition of rosemary. herb extract quench the fluorescence of etb...