Mutations in TSPAN7--a member of the tetraspanin protein superfamily--are implicated in some forms of X-linked intellectual disability. Here we show that TSPAN7 overexpression promotes the formation of filopodia and dendritic spines in cultured hippocampal neurons from embryonic rats, whereas TSPAN7 silencing reduces head size and stability of spines and AMPA receptor currents. Via its C termin...

Research Activity of the History Humanist and Social Thought Unit at Institute for Science PAS in 2021 The article presents main scope research, scientific achievements, popularization organizational accomplishments members 2021. research interests employees cover a wide variety topics, including institutional conditions development Polish science 20th century, intellectual movements currents, ...

Acentrally active drug that enhances AMPA receptor-mediated currents was tested for its effects on memory in humans. Evidence for a positive influence on encoding was obtained in four tests: (i) visual associations, (ii) recognition of odors, (iii) acquisition of a visuospatial maze, and (iv) location and identity of playing cards. The drug did not improve scores in a task requiring cued recall...

This article starts from the conceptions of education that contemplates real needs students with disabilities, and analysis practices teachers Multifunctional Resource Room municipal school network. Hence, a review in literature is presented, pointing out main currents traditional thought to current trends education. Allied these studies, concepts results research on assistive technology are po...

In his intellectual biography of the Jewish philosopher Martin Buber, A Life Faith and Dissent written in 2019, Paul Mendes-Flohr offers us an intimate view Buber’s life thought without neglecting story women their contributions to shaping thought. this short reflection essay, I wish present a crosscutting perspective on important by Mendes-Flohr, highlighting relation women, feminism, feminini...

abstract turbidity current is one of the most important factors that effect the sediments distribution and also their transportation and release from reservoir. in this study, effects of these currents on sedimentation process in sefidroud dam were simulated by tcm model in 30 years period. comparison between the case of turbidity currents that reach to the dam wall and release from the reservo...