The effect on aerosol deposition from a pressurised metered dose inhaler of a 750 cm3 spacer device with a one way inhalation valve (Nebuhaler, Astra Pharmaceuticals) was assessed by means of an in vivo radiotracer technique. Nine patients with obstructive lung disease took part in the study. The pattern of deposition associated with use of a metered dose inhaler alone was compared with that ac...

Accepted 27 May 1992 Abstract The amount ofbudesonide suspension actually delivered to six subjects (aged 4-30 months) by a jet nebuliser and spacer system (System 22) was determined. Two nebulisations were performed in each subject using a filter at the exhalation outlet of the inhalation chamber. An inhalation filter was additionally attached between the facemask and the spacer in the first t...

Hantaan, Seoul, and Puumala viruses were transmitted to 12-16-week-old female Wistar Rattus norvegicus by inhalation. The rodent infectious dose for each virus by intramuscular inoculation and by inhalation was determined, as was the infectious dose for Vero E-6 cells by direct plaque assay.

BACKGROUND Patients often experience problems using metered dose inhalers (MDIs), particularly poor coordination between inhalation start and dose actuation (TsIn: time difference between the start of an inhalation and the actuation of a dose), and fast peak inspiratory flow (PIF). We investigated if a coordination cap (CAP), with instruction to prolong inhalation, solved these problems. METH...

BACKGROUND Inhalation aids do not require coordination between actuation of a metered dose inhaler (MDI) with inspiration and reduce oropharyngeal impaction. The delivery of salbutamol to the lung and systemic availability following inhalation with three commonly used spacers and an open mouth technique have been evaluated using a simple noninvasive technique based on urinary excretion 30 minut...

The Rn and Rn enter the atmosphere mainly by crossing the air interface of either soil-air or building materials. The existence of relatively high indoor concentration maintains a large Rn, Rn concentration gradient between the materials and open air. The present paper deals with the experimental measurement of Rn, Rn concentrations and the associated inhalation dose rates due to them in the dw...

INTRODUCTION Mankind has been constantly exposed to radiation by natural radioactivity, nuclear tests, medical applications and nuclear energy activities. The natural radioactivity is the main component to human exposure and it is recognized that the most important contributors to the committed effective dose received by population due to natural sources are the short-lived decay products of ra...

The presence of radon in drinking water causes health risks associated with exposure from both inhalation and ingestion. Since the studies show that faults near the water resources have a critical effect on the concentration of radon, Kouhbanan active fault zone, to find water resources  with high radon concentration was chosen for the following investigation. Water samples were taken from all ...