conclusions clinical signs and symptoms presented by patients infected with the influenza a h1n1 virus were similar to those described for seasonal influenza, although with more gastrointestinal disorders. results among the 232 enrolled cases, 126 patients (54.31%) were male and 106 patients (45.89%) were female. real time reverse rt-pcr test revealed that 18.1% of suspected children were posit...

background in 2009, a pandemic associated with a new type of influenza a virus (h1n1) affected many countries worldwide. after five years of silence, in 2015 we encountered another outbreak of h1n1 influenza a. objectives the present study aimed to study the epidemiological and clinical features of this disease in the cold and dry climate of qazvin province, iran in the last epidemic, during 20...

background emergence of a novel swine-origin influenza a (h1n1) pandemic since 2009 attracted the attention of scientists to characterize epidemiological features and clinical manifestations of this disease in comparison to seasonal flu in different parts of the world. objectives the goal of this investigation was to compare these features in confirmed cases of swine-origin influenza a (h1n1) a...

conclusions: prevalence rate of h1n1 infection in the study region was higher compared to other part of iran; but, close to the expected rate. the h1n1-associated mortality rate was lower than the reported rates in iran and other parts of the world. background: khuzestan and other parts of iran were involved with influenza a (h1n1) pandemic in 2009. objectives: the aim of this study was to desc...

Background: Both influenza A virus (IAV) and respiratory syncytial virus (RSV) cause acute respiratory infection (ARI) in infants and young children. This study was conducted to determine Influenza A virus and its co infection with RSV among the hospitalized children with ARI. Methods: A total of 153 throat samples of the hospitalized young children aged between below one year and 5 years with...

Influenza viruses continue to be a major health threat in human and bird populations. The improvements in formulation and production level of the current influenza vaccines are not sufficient to afford complete protection. The continuous antigenic drifts and emergence of endemic and zoonotic strains make influenza vaccine planning difficult. Concern about the emergence of new influenza pandemic...

conclusions the prevalence of pandemic influenza viruses in recent years has caused financial losses as well as mortalities around the world. this shows the importance of the rapid diagnosis of common serotypes in our society. using real-time rt-pcr is recommended for the early diagnosis and the rapid identification of the individuals infected with pandemic influenza virus. background timely di...

respiratory virus infection is a major cause of asthma exacerbation. however, the underlying mechanisms of  this exacerbation  are unknown. therefore,  to  determine  the mechanisms, we examined the effect of influenza infection in a murine model of asthma.mice were divided into four groups: the phosphate-buffered saline (pbs), house dust mite (hdm), influenza, and hdm/influenza groups. the inf...

introduction: in recent years, influenza viruses have caused moderate to severe infections all around the world while so far there is no influenza vaccine that can protect people with only one dose of injection. in this regard, producing a universal vaccine based on virus-like-particles (vlp) could be an ideal approach.  methods: in this study, the full-length orf of influenza hemagglutinin (ha...