نتایج جستجو برای: inducing ligand
تعداد نتایج: 169340 فیلتر نتایج به سال:
Seven uranyl ion complexes have been crystallized under solvo-hydrothermal conditions from 2,5-thiophenedicarboxylic acid (tdcH2) and diverse additional, structure-directing species. [UO2(tdc)(DMF)] (1) is a two-stranded monoperiodic coordination polymer, while [PPh3Me][UO2(tdc)(HCOO)] (2) simple chain with terminal formate coligands. Although it also monoperiodic, [C(NH2)3][H2NMe2]2[(UO2)3(tdc...
چکیده کشت سلولهای بنیادی جنینی موش در بیش از 20 سال گذشته پیشرفت بزرگی را در بیولوژی و پزشکی به وجود آورده است. سلولهای بنیادی جنینی موش ، که دارای توانایی تکثیر دائمی میباشد ، از توده داخل 3 مشتق میگردند . یکی از جنبههای منحصر به فرد این سلولها ، امکان نگهداری / سلولی بلاستوسیت روز 5 به عنوان ردههای چند قوهای برای نسلهای مختلف است . این سلولهای بنیادی جنینی in vitro آنها در شرایط توانایی ...
Background: Members of the tumor necrosis factor (TNF) superfamily of ligands and their receptors (TNFR) are critical regulators of the adaptive immune system. A proliferation inducing ligand (APRIL) is a member of tumor necrosis factor superfamily. APRIL was identified via database mining in 1998 by Hahne, et al. APRIL allows tumor cells to proliferate at a reasonable rate even in low serum. A...
OBJECTIVES Herein, we determined the significance of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) in atherosclerotic vascular disease. BACKGROUND Inflammation is associated with the pathogenesis of atherosclerosis. The TNF-related apoptosis-inducing ligand/APO-2L, a member of the TNF superfamily, has a role in apoptosis induction and is recognized for its immunomodula...
When cells are exposed to death ligands such as TRAIL, a fraction undergoes apoptosis and a fraction survives; if surviving cells are re-exposed to TRAIL, fractional killing is once again observed. Therapeutic antibodies directed against TRAIL receptors also cause fractional killing, even at saturating concentrations, limiting their effectiveness. Fractional killing arises from cell-to-cell flu...
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