Introduction: Learning and memory processes result from interaction of neurotransmitter systems in various brain regions such as amygdala and hippocampus. Considering that morphine induces memory impairment, in the current study, we examined the possible role of cholinergic muscarinic receptor s of the central amygdala (CeA) on the morphine-induced amnesia in adult male Wistar rats. Methods: A ...

most serious problem that leads to reproductive system failure in both human and animals. Present study was carried out to investigate whether hydroalcholic extract of Dorema aucheri leaves could protect the male rats against lead-induced reproductive toxicity. Materials and Methods: Adult wistar rats were treated with 0.1% lead acetate in drinking water with or without 100, 200 and 400 mg/kg D...

background: epilepsy is a chief communal health problem. antiepileptic drugs only provide symptomatic treatment. walnut kernels (wk) have high concentrations of phenolic compounds, which have beneficial effects on human health because of their antioxidant and anti-atherogenic properties. the present study was designed to evaluate the efficacy of wk supplementation for the prevention of experime...

Introduction: Learning and memory processes result from interaction of neurotransmitter systems in various brain regions such as amygdala and hippocampus. Considering that morphine induces memory impairment, in the current study, we examined the possible role of cholinergic muscarinic receptors of the central amygdala (CeA) on the morphine-induced amnesia in adult male Wistar rats. Methods...

objective(s) high blood glucose induces molecular, cellular, morphological and behavioral changes in the brain. metabolic disturbances, contribute to the hippocampus injury and development of partial focal seizures. the aim of this study was to investigate the effects of infantile repeated hyperglycemia on neuronal density of hippocampal ca3region in newborn wistar male rats and its effect on c...

objective: it is generally agreed that most of the phenomena observed during brain ischemia and reperfusion can be explained by the damage to membrane structure. oxidative stress is resulted in an imbalance between high consumption of oxygen and low levels of endogenous antioxidants. it is known that gallic acid (ga) is a strong antioxidant. the present study was carried out to evaluate the eff...

introduction: the n-methyl-d-aspartate (nmda) receptors, which have been implicated in memory formation, could be noncompetitively blocked by ketamine. the present study examines the short term effect of ketamine on induction of anterograde and retrograde amnesia in male rats using morris water maze (mwm). methods: male n-mri rats were randomly divided into nine experimental groups. mwm studies...

evaluation of hypoglycemic activity of inflorescence of borassus flabellifer extract in male wistar rats has been investigated. antidiabetic potentials were studies by the orally administration of plant extract at the doses of 150, 300 and 600 mg/kg in streptozocin-induced diabetic male wistar rats. treatment of streptozocin-induced diabetic male wistar rats with the extracts caused a significa...