BACKGROUND Early coronary bypass graft failures may be preventable if identified intraoperatively. The purpose of this investigation was to compare the diagnostic accuracy of two intraoperative graft assessment techniques, transit-time ultrasound flow measurement and indocyanine green fluorescent-dye graft angiography. METHODS Patents undergoing isolated coronary artery bypass grafting with n...

OBJECTIVE To compare the anatomical and visual outcomes of primary idiopathic macular hole surgery using indocyanine green-assisted internal limiting membrane peeling versus no internal limiting membrane peeling. DESIGN Prospective randomised controlled clinical trial. SETTING University teaching hospital, Hong Kong. PATIENTS Fifty-one eyes of 49 Chinese patients with primary idiopathic m...

Indocyanine green 1 (ICG) is a tricarbocyanine dye (Figure 1) which has been used in the indicator dilution technique for measuring cardiac output (1, 2). Animal studies (3) and preliminary observations of human subjects (4, 5) have suggested that this dye may have characteristics that could make its uptake, storage, and excretion by the liver helpful indices of hepatic function. The present in...

PURPOSE Because of the potential usefulness of evaluating and treating choroidal neovascularization obscured by blood, we designed this study to quantify the transmission of dye fluorescence and laser energy through blood. METHODS Blood preparations anticoagulated with ethylenediaminetetraacetic acid with hematocrits of 0% (plasma), 46%, and 99% were placed in open cuvettes with path lengths ...

Hepatic ischaemia/reperfusion (I/R) injury is a major cause of primary non-function of the graft after liver transplantation. The ability to assess the severity of ischaemic injury would be of prognostic value and allow the possibility of therapeutic interventions. Currently there is no reliable clinical method for assessing the severity of hepatic ischaemic injury. The hepatic handling of Indo...

T he concept of retinal vital staining is not new. There has however been renewed interest in the subject since indocyanine green (ICG) was introduced as a vital stain to highlight the internal limiting membrane (ILM) during macular surgery. ICG’s well known role in cardiac and choroidal angiography exploits its properties as a fluorophore, but its role as a macular vital stain relies on its pr...

A brief survey of the recent ophthalmic literature underscores a resurgence of interest in indocyanine green angiography (ICGA). This imaging method may be particularly useful for the ophthalmologist, as it provides at least a theoretical advantage for improved imaging of the choroidal circulation when compared with fluorescein angiography. New temporal and spatial technological advances (that ...