HYPOTHESIS A number of risk factors for incisional hernia have been identified, but the pathogenesis remains unclear. Based on previous findings of smoking as a risk factor for wound complications and recurrence of groin hernia, we studied whether smoking is associated with incisional hernia. DESIGN Cohort study. Clinical follow-up study for incisional hernia 33 to 57 months following laparot...

aloe littoralis baker (asphodelaceae family) is a well known plant in southern parts of iran. because of its use in iranian traditional medicine as a wound-healing agent, the present study was carried out to investigate anti-inflammatory and wound healing activities of this plant in wistar rats. a. littoralis raw mucilaginous gel (alrmg) and also two gel formulations prepared from the raw mucil...

BACKGROUND Emergency repair of incarcerated incisional hernia with associated bowel obstruction in potentially or contaminated field is technically challenging due to edematous, inflamed and friable tissues with occasional need for concurrent bowel resection and carries high rates of post-operative infectious complications. The aim of this study was to retrospectively assess the wound related m...

OBJECTIVE Acute wound failure is a common complication following surgical procedures and trauma. Laparotomy wound failure leads to abdominal dehiscence and incisional hernia formation. Delayed recovery of wound-breaking strength is one mechanism for laparotomy wound failure. Early fascial wounds are relatively acellular, and there is a delay in the appearance of acute wound growth factors and c...

introduction: the effectiveness of low power lasers for incisional wound healing, because of conflicting results of previous research studies, is uncertain. therefore, this study was carried out to evaluate low power laser effects on incisional wound healing. materials and methods: incisional wound was produced on thirty-six mature male guinea pigs under general and local anesthesia. in half of...

Morbid obesity is another important risk factor for the development of an incisional hernia and a parastomal hernia [9, 10]. Schreinemacher et al. [9] reported that hernias were more prevalent in patients with morbid obesity (body mass index of 30 and higher) and in patients with a temporary stoma wound (25.8% vs. 59.1%). De Raet et al. [10] reported that a waist circumference in excess of 100 ...

HYPOTHESIS In midline incisions closed with a single-layer running suture, the rate of wound complications is lower when a suture length to wound length ratio of at least 4 is accomplished with a short stitch length rather than with a long one. DESIGN Prospective randomized controlled trial. SETTING Surgical department. PATIENTS Patients operated on through a midline incision. INTERVENT...

Mac-1 (CD11b/CD18) is a macrophage receptor that plays several critical roles in macrophage recruitment and activation. Because macrophages are essential for proper wound healing, the impact of Mac-1 deficiency on wound healing is of significant interest. Prior studies have shown that Mac-1-/- mice exhibit deficits in healing, including delayed wound closure in scalp and ear wounds. This study ...

Roux-en-y gastric bypass (RYGB) has become the most common operation in the United States for morbid obesity. Even in the laparoscopic era many procedures are still done via laparotomy. Incisional hernias are a complication of any abdominal surgery with obese patients being at increased risk. Patients undergoing open RYGB over 6 years were reviewed to evaluate the risk factors for the developme...

Objective: To determine the effects of bone marrow derived mast cells (BMMCs) on excisional and incisional wound healing in an animal model on lamb.Design- Experimental Study.Animals- Twelve healthy male lambsProcedures: Animals were randomized into four groups of three animals each. In CONTROL animals, the created wounds were left untreated receiving 100 μL PBS. In BMMC group...