conclusions it is concluded that most hbeag negative hepatitis b patients with serum hbv dna level of 2000-20000 iu/ml, persistent normal alt concentration, and no or mild liver damage on biopsy can be clinically managed as hbv inactive carriers. results two hundred forty-three hbeag negative hepatitis b patients were stratified into three groups based on to their hbv dna level including group ...

Wiskott-Aldrich syndrome (WAS) is an X-linked immunodeficiency disorder with no clinical or immunologic abnormalities in carrier famales. The defective gene has been localized to proximal Xp. Carrier females have nonrandom use of the X chromosome in granulocytes, lymphocytes, and monocytes. We have used the probe M27p. which detects both a variable number tandem repeat polymorphism and methylat...

The transport activity of the lactose carrier of Escherichia coli has been reconstituted in proteoliposomes composed of different phospholipids. The maximal activity was observed with the natural E. coli lipid as well as mixtures containing phosphatidylethanolamine or phosphatidylserine. Phosphatidylcholine or mixtures of phosphatidylcholine with phosphatidylglycerol, phosphatidic acid, or card...

Background and Aims: During recent years, the relationship between vitamin D levels and chronic hepatitis B (CHB) infection has attracted many researchers' attention. However, the results relating to the association of vitamin D levels and HBV infection have been conflicting and there remains a lack of knowledge about the effects of antiviral treatments on vitamin D level. Methods: Eighty-four ...

BACKGROUND The differential diagnosis between inactive carrier and active hepatitis is important in patients with chronic hepatitis B (CHB) virus infection. Serum cytokeratin (CK)-18 fragments (M30-antigen) are proposed as biomarkers of apoptosis. OBJECTIVES We investigated whether serum M30-antigen levels might help to characterize the various phases of CHB and predict the state of significa...

conclusions fluctuations in serum alt levels may change the prognosis of a hbv inactive carrier state. objectives this study aimed to determine the incidence rate and patterns of alt fluctuations and prognostic values for the development of chronic hbv e antigen (hbeag)-negative hepatitis b (chb), hbv surface antigen (hbsag) seroclearance, and liver-related complications. patients and methods t...

Hepatitis B virus (HBV) may be reactivated after chemotherapy or immunosuppressive therapy, and therefore administration of antiviral agents before such treatment is recommended. Most reported cases of reactivation are associated with high doses of immunosuppressive agents or combination therapy. We present a case of a previously inactive HBV carrier with an acute severe flare-up during a long-...

t o b The so-called inactive carriers are regularly revisited in hepatologist’s literature, but many pending issues are yet unsolved. Magalhães et al looked back in to a cohort of patients carefully followed with serial assessment of some blood parameters, trying to indirectly validate their own strategy of monitoring. Patients infected with hepatitis B virus (HBV) present several patterns of s...

Idiopathic portal hypertension belongs to the group of non-cirrhotic portal hypertension, its etiology is still unknown but its prognosis is excellent. We report a case of 45 year old female with inactive hepatitis B virus (HBV) carrier status and persistently elevated alpha-fetoprotein (AFP), presented with features of portal hypertension and without evidence of cirrhosis or fibrosis on liver ...

Oligonucleotide-streptolysin S complex inactivated by alkali treatment remains nonhemolytic, even after acidification and mixing with intact carrier oligonucleotide rich in guanyl residue. Upon dehydration, however, the inactive streptolysin S-oligonucleotide mixture turned to be hemolytic, and this reactivation of the hemolysin was promoted by treatment with guanidine hydrochloride. After alka...