Several adult reptiles, such as Gekko japonicus, have the ability to precisely re-create a missing tail after amputation. To ascertain the associated acquisition of positional information from blastemal cells and the underlying molecular mechanism of tail regeneration, a candidate molecule CD59 was isolated from gecko. CD59 transcripts displayed a graded expression in the adult gecko spinal cor...

koelreuteria elegans, popularly known as “flame gold” is an ornamental tree. in vitro callus induction and regeneration from various explants (eaf segments and cotyledonary leaf) were studied on modified ms medium. the highest callus induction rate (80%) and multiplication was obtained in 2 mg/l 2,4-d from leaf segments. calli transferred in 1.5 mg/l bap resulted in efficient shoot regeneration...

Hierarchical calcium carbonate structures with multi-scale organization have been successfully fabricated covering the full range of pore sizes from nano-, to micro- to macrofeatures. The resulting 3D scaffolds, with a close resemblance to bone structures, have been evaluated in vitro and in vivo and showed great potential for bone regeneration.

It has been well recognized that the modification of biomaterials with appropriate bioactive peptides could further enhance their functions. Especially, it has been shown that peptide-modified bone repair materials could promote new bone formation more efficiently compared with conventional ones. The purpose of this article is to give a general review of recent studies on bioactive peptide-modi...

Severed axons of the inferior colliculus (IC) commissure can regenerate across a lesion in organotypic cultures from postnatal day (P) 6 gerbils, but this regenerative capacity is lost by P12 (Hafidi et al. [ 1995] J Neurosci 15:1298-1307, [1999] J Neurobiol 41:267-280). In the present study, we examined the mechanisms underlying this age-dependent failure of axons to regenerate. In P6-P12 hete...

New regenerative materials and approaches need to be assessed through reliable and comparable methods for rapid translation to the clinic. There is a considerable need for proven in vitro assays that are able to reduce the burden on animal testing, by allowing assessment of biomaterial utility predictive of the results currently obtained through in vivo studies. The purpose of this multicentre ...

Koelreuteria elegans, popularly known as “Flame Gold” is an ornamental tree. In vitro callus induction and regeneration from various explants (eaf segments and cotyledonary leaf) were studied on modified MS medium. The highest callus induction rate (80%) and multiplication was obtained in 2 mg/l 2,4-D from leaf segments. Calli transferred in 1.5 mg/l BAP resulted in efficient shoot regeneration...

In this edition of COGEDE, we have invited colleagues to contribute their unique perspectives to illustrate the diverse ways that reprogramming is used in biology. This includes studying or harnessing reprogramming in various model systems as well as different experimental and natural contexts. Our goal is to demonstrate that reprogramming is not restricted to one stage of life, and it is not e...