After their cytoplasmic synthesis, ribosomal proteins need to be transported into the nucleus, where they assemble with ribosomal RNA into pre-ribosomal particles. Due to their physicochemical properties, they need protection from aggregation on this path. Newly synthesized ribosomal protein Rps3 forms a dimer that is associated with one molecule of its specific chaperone Yar1. Here we report t...

Two peroxisome targeting signals (PTSs) for matrix proteins have been well defined to date. PTS1 comprises a COOH-terminal tripeptide, SKL, and has been found in several matrix proteins, whereas PTS2 has been found only in peroxisomal thiolase and is contained within an NH2-terminal cleavable presequence. We have investigated the functional integrity of the import routes for PTS1 and PTS2 in fi...

The objective of this paper is to quantify Lobbying Effectiveness for trade policy. I introduce this measure into Grossman and Helpman’s (1994, American Economic Review 84: 833–850) model of protection-for-sale (PFS). Two alternate factors are suggested to explain differences in lobbying effectiveness across sectors; first, predisposition of the government to supply protection (owing arguably t...

AIMS Protein kinase C epsilon (PKCepsilon) is critical for cardiac protection from ischaemia and reperfusion (IR) injury. PKCepsilon substrates that mediate cytoprotection reside in the mitochondria. However, the mechanism enabling mitochondrial translocation and import of PKCepsilon to enable phosphorylation of these substrates is not known. Heat shock protein 90 (HSP90) is a cytoprotective pr...

Available online 8 October 2011 We empirically examine the impact of trade on labor demand elasticities using Korean firmlevel data. In our analysis, in addition to looking at the impact of liberalizing import restrictions, we take into account the fact that greater trade integration also leads to better and greater export possibilities. While we find that Korea's own tariffs do not have any st...

this paper aims to analyze tariff protection policies in the agricultural sector of developing countries. the agricultural tariff structure in developing countries is characterized by: i) high average tariffs, ii) the existence of tariff escalation, iii) dispersion of nominal tariffs across tariff lines, and iv) a wide gap between average nominal tariffs and import-weighted average tariffs. con...

In this paper, we investigate endogenous foreign direct investment incentives in an export sector when the tari is exogenously given. Using a cost-bene t rule to determine exportinvestment incentives, authorities are shown to set subsidies which neutralize the e ects of tari s and which correspond to their welfare-maximizing level. Extending the model to two countries, we show that, depending o...

Tariff bindings and administered protection are two characteristics of the WTO that are little understood. Tariff bindings place a ceiling on tariffs that is not always reached, while administered protection ensures that all sectors have access to some minimum import protection, effectively creating a floor for protection. How do these policies affect applied MFN tariff rates that are enacted t...