The RNA-binding protein HuR binds to elements rich in adenylate and uridylate (AU-rich elements) in target mRNAs and stabilizes them against degradation. The complete spectrum of genes whose expression is regulated by HuR and are the basis for the broad range of cellular functions of the protein is incompletely understood. We show that HuR controls the expression of multiple components of the n...

Mitochondrial dysfunction is a contributor to diabetic cardiomyopathy. Previously, we observed proteomic decrements within the inner mitochondrial membrane (IMM) and matrix of diabetic cardiac interfibrillar mitochondria (IFM) correlating with dysfunctional mitochondrial protein import. The goal of this study was to determine whether overexpression of mitochondria phospholipid hydroperoxide glu...

BACKGROUND Between 1950 and 1995 suicide rates in Sri Lanka increased 8-fold to a peak of 47 per 100,000 in 1995. By 2005, rates had halved. We investigated whether Sri Lanka's regulatory controls on the import and sale of pesticides that are particularly toxic to humans were responsible for these changes in the incidence of suicide. METHODS Ecological analysis using graphical and descriptive...

according to amount of oil seeds import in iran are more than 80% of domestic needs, in this study, import comparative advantage in soybeans using rca and rsca index is calculated in 1961-2008 periods for iran and ten important importer countries. iran’s competition state is investigated. also long run relation between production and import comparative advantage index is estimated using johanse...

one of the import indices of food security evaluation is food import capacity index. ratio of total exports to food imports is often thought to be a measure of the capacity of a country to finance its food imports using revenues from exports of goods and services. this study investigates food import capacity effects on rural households food security by calculated ahfci (aggregate household food...

due to the importance of the import management, this study applies generalized ardl approach to estimate midas regression for wheat import value and to compare the accuracy of forecasts with those competed by the regression with adjusted data model. mixed frequency sampling models aim to extract information with high frequency indicators so that independent variables with lower frequencies are ...

Abstract. The northern Barents Sea is a cold, seasonally ice-covered Arctic shelf sea region that has experienced major warming and ice loss in recent decades. Here, 2-year observational record from two ocean moorings provides new knowledge about the seasonal hydrographic variability exchange across its margin. combined records of temperature, salinity, currents show advection warmer saltier wa...