BACKGROUND Immunosuppression for solid organ transplantation is associated with increased incidence of internal and cutaneous malignant tumors, among which skin cancer is the most common. OBJECTIVE To determine the effects on cutaneous carcinogenesis when stopping therapy with immunosuppressive medications. OBSERVATIONS We followed the clinical course of 6 solid organ transplant recipients ...

Automated dispensing cabinets (ADCs)—now ubiquitous in U.S. hospitals—also play a large role in the medication administration process. Managing Time-Critical Medications Promoting patient safety includes complying with CMS requirements regarding the medication use process. One of these requirements calls for dispensing and administering time-critical medications within a 30-minute window. Antib...

BACKGROUND An increasing number of patients have medical conditions with altered host immunity or that require immunosuppressive medications. While immunosuppression is associated with increased risk of infection, the precise effect of immunosuppression on innate immunity is not well understood. We studied monocyte Toll-like receptor (TLR) expression and cytokine production in 137 patients with...

At a time when the judicious use of a broad range of immunosuppressive drugs has ensured excellent patient and organ survival rates after kidney transplantation, attention is focusing on strategies to minimize their side effects. Almost all immunosuppressive medications are associated with some form of gastrointestinal (GI) complication (1–6). The majority of these complications fall into one o...