نتایج جستجو برای: immunologic desensitization
تعداد نتایج: 37840 فیلتر نتایج به سال:
Immunotherapy in allergic fungal sinusitis: The controversy continues. A recent review of literature
Allergic fungal sinusitis (AFS), also referred to as allergic fungal rhinosinusitis (AFRS), is a noninvasive, eosinophilic form of recurrent chronic allergic hypertrophic rhinosinusitis. AFS has distinct clinical, histopathological, and prognostic findings that differentiate it from other forms of sinusitis. The core pathogenesis and optimum treatment strategies remain debated. Concerns surroun...
The detrimental effects of donor-directed antibodies in sensitized transplant patients remain a difficult immunologic barrier to successful organ transplantation. Antibody removal is often followed by rebound. Proteasome inhibitors (PIs) deplete antibody-producing plasma cells (PCs) but have shown marginal benefit for desensitization. In an allosensitized nonhuman primate (NHP) model, we observ...
As the need for the organ donation increases, strategies to increase kidney transplantation (KT) through expanded living donation have become essential. These include kidney paired donation (KPD) programs and desensitization in incompatible transplantations. KPD enables kidney transplant candidates with incompatible living donors to join a registry with other incompatible pairs in order to find...
Colorectal cancer (CRC) is the third-leading cause of cancer death in the United States. With the advent of new chemotherapy drugs, such as oxaliplatin, for CRC, disease-free and long-term survival has improved in this patient population. As oxaliplatin use increases, more hypersensitivity reactions may be expected. The etiology of these reactions is unclear but may be a combination of immunolo...
Antibodies to donor-specific HLA antigens (donor-specific antibodies [DSA]) detected by single-antigen bead (SAB) analysis prior to kidney transplant have been associated with inferior graft outcomes. However, studies of pretransplant DSA, specifically in the setting of a negative flow cytometry crossmatch (FCXM) without desensitization therapy, are limited. Six hundred and sixty kidney and kid...
BACKGROUND Peanut allergy is an increasingly common health problem. Current treatment guidelines are based on strict avoidance. However, in the last few years, oral immunotherapy protocols have shown promising results yielding increased tolerance to peanut in allergic children. Adolescence is particularly at risk. METHODS/DESIGN We have designed a randomized, double-blind, placebo-controlled,...
Abstract Background Immediate hypersensitivity reaction to ursodiol is rare and there no previously published protocol on desensitization. Case presentation A 59-year-old woman with primary biliary cholangitis (PBC) developed an immediate ursodiol—the first-line treatment for PBC. When she switched a second-line treatment, her PBC continued progress. As such, completed novel 12-step desensitiza...
Although a variety of treatments have been developed over the past decade to treat post-traumatic stress disorder (PTSD), one of the most effective psychological treatments to improve its symptoms is eye movement desensitization and reprocessing (EMDR). This study was performed with the aim to systematically review the studies which have focused on the effect of eye movement desensitization and...
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