Autoimmunity and immune dysregulation may lead to cytopenia and represent key features of many primary immunodeficiencies (PIDs). Especially when cytopenia is the initial symptom of a PID, the order and depth of diagnostic steps have to be performed in accordance with both an immunologic and a hematologic approach and will help exclude disorders such as systemic lupus erythematosus, common vari...

The incidence of suicide in patients with the diagnosis of acquired immunodeficiency syndrome (AIDS) in the state of Texas during the period between January 1986 and August 1987 was determined. AIDS patients were found to have a rate of suicide higher than expected when compared to the general population. The results of this study document this trend which has important implications in the care...

There are many challenges to those who specialize in the research, education, and clinical care of patients with primary immunodeficiency. The first of these difficult challenges is just keeping up with this rapidly moving area of medicine, a task that is obvious to those who are engaged in the ongoing discoveries of genetic mutations causing previously unrecognized primary immunodeficiencies. ...