Objective. Bullous pemphigoid is well known for its cutaneous features; however in rare cases it may present with mucosal involvement. We report a case of bullous pemphigoid presenting with haemoptysis, initially presenting to the Ear, Nose and Throat Department for investigation. Methods. An 87-year-old lady was admitted with haemoptysis. She also complained of a spreading, pruritic, bullous r...

Immunofluorescence is an immunological method used to demonstrate the presence of antigen and antibodies in tissues or serum. Immunofluorescence techniques have become indispensable in modern pathology laboratories and have greatly contributed to the diagnosis, treatment and understanding of autoimmune bullous diseases, hereditary bullous diseases, collagen-vascular diseases, many inflammatory ...

Background: Immunobullous diseases are morphologically heterogeneous and the differentiation between various subtypes is essential for proper treatment and prognosis. The aim of our study was to analyze and correlate clinical, histopathological, and immunofluorescence findings in autoimmune bullous diseases.Method: A c...

IMPORTANCE Immunobullous diseases mediated by IgA are often difficult to manage, but to date no mechanism has been proposed. Rituximab is an anti-CD20 monoclonal antibody that has demonstrated good efficacy in the treatment of refractory mucous membrane pemphigoid. However, not all cases of mucous membrane pemphigoid respond to rituximab. Herein we present a case of treatment-refractory mucous ...

OBJECTIVE To evaluate the efficacy and safety of oral alendronate sodium therapy once daily in preventing glucocorticoid-induced bone loss in patients with immunobullous skin diseases treated with long-term glucocorticoid therapy. DESIGN A 12-month randomized, double-blind, placebo-controlled trial. SETTING A tertiary referral dermatology center in Singapore. PARTICIPANTS Patients newly d...