In this position paper, we outline a vision for a new type of engineering: immuno-engineering, that can be used for the development of biologically grounded and theoretically understood Artificial Immune Systems (AIS). We argue that, like many bio-inspired paradigms, AIS have drifted somewhat away from the source of inspiration. We also argue that through an interdisciplinary approach, it is po...

Disc immuno-immobilization is a simple method for typing the flagellar phase of Salmonella enterica. We re-examined this method using commercial antisera, which contains the preservative sodium azide. Originally prepared motility agar activates bacterial motility and renders S. enterica resistant to sodium azide, resulting in the formation of immuno-immobilization lines around reactive immuno-d...

<abstract><p>This study addresses a cancer eradication model involving effector cells in the presence of gene therapy, immunotherapy, and chemotherapy. The main objective this is to understand optimal effect immuno-chemotherpay therapy. boundedness positiveness solutions respective feasible domains proposed are verified. Conditions for which equilibrium points system exist stable ha...

Immunotherapy is a promising strategy for the treatment of human epidermal growth factor receptor 2 (HER2)-positive tumors. Previously, we constructed an immuno-carboxy terminal fragment of Bid (immuno-tBid) and reported its specific and effective destruction of HER2-positive tumor cells. In this study, in order to further reduce the immunogenicity of the previous immuno-proapoptotic protein, w...

Excessive immune responses directed against foreign pathogens, self-antigens, or commensal microflora can cause cancer establishment and progression if the execution of tight immuno-regulatory mechanisms fails. On the other hand, induction of potent tumor antigen-specific immune responses together with stimulation of the innate immune system is a pre-requisite for effective anti-tumor immunity,...