ae is a serious medical condition in which the immune system attacks the brain, impairing function. with rapid diagnosis and appropriate treatment, many patients recover most or all functions. however, not all patients experience full recovery; with approximately 6% mortality and other patients who never regain significant brain and/or bodily functions. autoimmune encephalitis can produce a wid...

twik2 ion channels (k2p6.1, encoded by a gene named kcnk6) belong to the family of two-pore domain potassium channels. twik2 is also considered as a “silent” channel because of its inability to produce measurable currents in heterologous expression systems and its intracellular retention. it is expressed in different mammalian tissues including lymphoid organs and the vascular system. however, ...

the aim of this study was to evaluate the immune system and lymphocyte function in 41 iranian β-thalassemic patients and 50 controls, ages ranging from 2 to 18 years. the patients consisted of 20 splenectomized and 21 non-splenectomized patients. they were treated with desferal, and had received repeated blood transfusion. laboratory investigations included measurement of total t lymphocytes, a...

background: immune thrombocytopenia is a hematologic disorder characterized by low platelet count and variable bleeding manifestations due to immune-mediated platelet destruction and/or suppression of platelet production. this study was performed to evaluate characteristics and clinical presentations of adult patients with immune thrombocytopenia and to explore the clinical value of platelet an...

skeletal muscle may develop adaptive chaperone and enhancementdefense system through daily exercisestimulation. the present study investigated resistance and exhaustion training alters the expression of chaperoneproteins. these proteins function to maintain homeostasis, facilitate repair from injury and provide protection. exercise-induced production of hsps in skeletal muscle and peripheral le...

this study was conducted to investigate the effects of artichoke powder on performance and immune function of japanese quails poisoned with carbon tetrachloride (ccl4). one hundred meat type (1-d-old) quails were assigned randomly to 4 treatment groups (n=25). treatment groups included with the study were: 1) control group (without artichoke supplementation or ccl4 administration, 2) group with...

twenty pregnant buffaloes, eight weeks before the expected calving date, were assigned into two homogeneous groups of 10 animals each, according to their season of lactation (2nd to 8th season of lactation); the first group (g1) were fed on a ration consisting of concentrate feed mixture (22% yellow corn, 35% cotton seed meal, 33% wheat bran, 4% rice bran, 3% molasses, 2% limestone and 1% sodiu...

abstract background: exercise could change the immune system. it is illustrated that abnormal environments are the primary source of physiological stresses which can disarrange the function of immune system. the purpose of this study was to investigate the effects of high volume exercise (hve) in hypoxia and normoxia conduction on the immune system response in selected inactive men. materials a...

this study was conducted to compare the effects of diets borage powder and control (no additives diets) on broiler’s average blood cell counts and immune system on the broiler chicks. sixty four male broiler chicks (ross 308) randomly allocated into one of two treatments with four replicates of eight chickens based on a completely randomized block design.  diets were include control (no additiv...

gene association studies are less appealing in cancer compared to autoimmune diseases. complexity, heterogeneity, variation in histological types, age at onset, short survival, and acute versus chronic conditions are cancer related factors which are different from an organ specific autoimmune disease, such as grave’s disease, on which a large body of multicentre data is accumulated. for years t...