The aim of this study was to determine both the occurrence and the genetic basis of resistance to erythromycin among 1 235 Staphylococcus spp. isolates obtained between 2000 and 2006 from (a) raw milk and meat (1 704 samples), (b) foodstuffs produced from these (451 samples), and (c) contact surfaces at processing plants and dairy farms (363 samples) in the Czech Republic. Isolates were screene...

Erythromycin and clindamycin are major alternatives to βlactam antibiotics. Bacterial resistance to macrolide and lincosamide antibiotics is increasing worldwide. Erm genes express either constitutive macrolide, lincosamide streptogramin B resistance phenotype (cMLSB) or inducible phenotype (iMLSB) and msrA gene expresses (MSB) phenotype. The aim of this study was to determine the frequency of ...

conclusions the rate of imlsb in s. aureus isolates is relatively high in the northwest iran. since isolates with inducible resistance may mutate and change to constitutive resistance, to prevent clinical treatment failure, d-test should be performed along with routine antibiotic susceptibility tests. in this study, ermc gene was the predominant genetic determinant for the expression of mlsb re...

background antibiotic resistance among staphylococcus aureus is of great concern worldwide. this resistance is further complicated by the ability of s. aureus to confer cross-resistance to other antibiotics due to the presence of resistance genes, such as erythromycin resistance methylase (erm) genes, which render the bacterium resistant to macrolide-lincosamide-streptogramin b (mlsb) antibioti...

Against the backdrop of ever-changing Staphylococcal resistance pattern, clindamycin remains a viable therapeutic alternative Variation Clindamycin drug patterns with geographic area make inducible testing imperative for all staphylococcal isolates to avoid failure. This was prospective study conducted over period 1.5 years from January 2021 until June 2022. Prevalence different MLSB Phenotypes...

background: macrolides, lincosamides and type b streptogramins (mlsb) are commonly used for the treatment of staphylococcal infections. inducible mlsb resistance (imlsb) cannot be identified by standard methods of antibiotic susceptibility testing. d-test appears to be a reliable indicator of imlsb strains. the aim of this study was to determine the prevalence of clindamycin resistance phenotyp...