Glutamic Semialdehyde, Synthesis, Reactivity, Glutamic Acid, Derivatives Glutamic-1-semialdehyde which is discussed to be involved in the early steps of chlorophyll biosynthesis, has been synthesized from glutamic acid by reduction of several N-protected carboxylic acid derivatives like the N-CBO-glutamic acid-1-dimethyl amide or methylanilide, the pyroglutamic acid imidazolide and the acid chl...

Synthetic triterpenoids, CDDO (2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid) or CDDO-imidazolide [2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid imidazolide (CDDO-Im)], induce cell differentiation in myeloid leukemia cells but their mechanism of action is not known. CDDO-Im induces monocytic differentiation markers, CD14, and nonspecific esterase in HL60 leukemia cells. We show that CDDO-Im act...

An improved method for the partial chemical synthesis of unsaturated and radioactively labeled phosphatidylcholines is described. This procedure offers advantages over conventional acylation methods in that it can be carried out on a millimole or micromole scale under mild conditions and it does not require a large excess of the fatty acid acylating reagent. In this procedure sn-glycero-3-phosp...

The title compound, [Co(C(18)H(23)N(10))](BF(4))(2) x H(2)O, is the result of complexing a Co cation (initially in a Co(II) state) with tris[2-(1H-imidazol-2-ylmethyleneamino)ethyl]amine (L), obtained by a condensation process involving imidazole-2-carbaldehyde and tris(2-aminoethyl)amine. Both the Co cation and the ligand were modified in the synthesis process, the cation via oxidation to Co(I...