Preventive healthcare aims at reducing the likelihood and severity of potentially life-threatening illnesses by protection and early detection. In this paper, a bi-objective mathematical model is proposed to design a network of preventive healthcare facilities so as to minimize total travel and waiting time as well as establishment and staffing cost. Moreover, each facility acts as M/M/1 queuin...

Streptococcus mutans, a Gram-positive bacterium, is considered to be a major etiologic agent of human dental caries and reported to form biofilms known as dental plaque on tooth surfaces. This organism is also known to possess a large number of transport proteins in the cell membrane for export and import of molecules. Nitrogen is an essential nutrient for Gram-positive bacteria, though alterna...

Bacillus subtilis uses glutamine as the best source of nitrogen. In the absence of glutamine, alternative nitrogen sources such as ammonium can be used. Ammonium utilization involves the uptake of the gas or the ammonium ion, the synthesis of glutamine by the glutamine synthetase and the recycling of the glutamate by the glutamate synthase. In this work, ammonium transport in B. subtilis was st...

in this paper, a novel mathematical model for a preemption multi-mode multi-objective resource-constrained project scheduling problem with distinct due dates and positive and negative cash flows is presented. although optimization of bi-objective problems with due dates is an essential feature of real projects, little effort has been made in studying the p-mmrcpsp while due dates are included i...

Integrating flexible job-shop scheduling problem (FJSP) with preventive maintenance (PM) is pondered in this paper. Minimizing the makespan for scheduling part and minimizing the system unavailability for maintenance part are simultaneously under consideration. For doing it, the assignment of n jobs on m machines in production side and executing the PM actions at appropriate time intervals in m...

in this study, a bi-objective model for integrated planning of production-distribution in a multi-level supply chain network with multiple product types and multi time periods is presented. the supply chain network including manufacturers, distribution centers, retailers and final customers is proposed. the proposed model minimizes the total supply chain costs and transforming time of products ...

In this research, a bi-objective scheduling problem with controllable processing times on identical parallel machines is investigated. The direction of this paper is mainly motivated by the adoption of the just-in-time (JIT) philosophy on identical parallel machines in terms of bi-objective approach, where the job processing times are controllable. The aim of this study is to simultaneously min...

In this paper, the energy absorption features of tri-layer explosive-welded deep-drawn cups subjected to quasi-static axial compressive loading are investigated numerically and experimentally. To produce the cups, tri-layer blanks composed of aluminum and stainless steel alloys were fabricated by an explosive-welding process and formed by a deep drawing setup. The quasi-static tests were carrie...

In this paper, a novel mathematical model for a preemption multi-mode multi-objective resource-constrained project scheduling problem with distinct due dates and positive and negative cash flows is presented. Although optimization of bi-objective problems with due dates is an essential feature of real projects, little effort has been made in studying the P-MMRCPSP while due dates are included i...