The intraocular pressures of a total of 286 eyes of patients with lepromatous and borderline lepromatous leprosy who never had regular ophthalmological care or local eye treatment were measured. The patients were categorised according to the type of leprosy they had, and the eyes were categorised as without or with chronic plastic iridocyclitis. In patients with lepromatous and borderline lepro...

Histoid leprosy is a variant of lepromatous leprosy, which develops as a result of resistance to dapsone monotherapy. Here we report two cases of lepromatous leprosy of histoid type, one with typical and another with atypical presentations.

I. HISTORICAL II. IMPORTANCE OF THE TUBERCULOID FORM III. THE SOUTH AMERICAN CLASSIFICATION IV. COMMENTS ON SOUTH AMERICAN CLASSIFICATION 1. The question of transformation from the tuberculoid to the lepromatous type. 2. The difficulty of clinically differ entiating the neural cases. V. THE NATURAL COURSE OF THE INFECTION IN LEPROSY VI. A FOURTH FUNDAME NTAL TYPE OF LEPROSY VII. A PROPOSED MODI...

The serum concentrations of lactoferrin were determined by competitive enzyme immunoassay in the sera of 38 lepromatous leprosy patients and 16 healthy volunteers. Of the 38 lepromatous patients, 25 were without any sign of reactions while 13 were suffering from ENL type of reactions. The lactoferrin levels, in both types of patients, were observed to be significantly higher (P < 0.01 and < 0.0...

Su mmary. The fine structural changes and, to a lesser extent, histochemical and histopathological features of biopsy specimens of nerves from patients with non-lepromatous leprosy ( mainly very early cases) , or lepromatous leprosy (mostly treated cases) , have been studied from the point of view of possible immunological response of the host tissues. Using electronmicro­ scopy and acid phosph...

Lepromatous leprosy and sarcoidosis have varied clinical manifestations. These two diseases are sometimes mistaken for each other in their clinical, histopathological laboratory parameters, but coexistence is seemingly quite rare paradoxical. We present a 40-year-old female with newly diagnosed lepromatous subcutaneous sarcoidosis.

OBJECTIVES The primary objective of this retrospective study was to determine the prevalence of leprosy in families, and the secondary objective was to study the clinicoepidemiological features of leprosy in families. RESULTS There were a total of 901 cases of leprosy who attended our leprosy centre during this 18 year period. There were 49 cases of leprosy in this group whose family members ...

UNLABELLED INTRODUCTION; Cutaneous leishmaniasis is endemic in Sri Lanka. The immunopathogenesis of these lesions in Sri Lankans has not been documented. OBJECTIVES To classify skin lesions into histological groups, to assess parasitic load, density of each inflammatory cell type and necrosis and to characterise the lymphocytic reaction in cutaneous leishmaniasis in comparison to leprosy. M...

Following O'Byrne's report ( If)) of the efficacy of antithyroid drugs in leprosy, an examination of the mechanism of action of methimazole in lepromatous leprosy was undertaken. In a preliminary report of this study (n), a lack of correspondence was noted be tween the clinical appearance of the patients and the histopathologic appearance of serial skin biopsies obtained during methimazole ther...

Lymphadenopathy is known to be associated with lepromatous leprosy and has also been observed as a feature of type-2 lepra reaction. However, nodular lymph node enlargement is not commonly reported in leprosy patients or as a feature of relapse. We herewith are presenting a case of bacteriological relapse in a patient of lepromatous leprosy treated 22 years before till smear negativity with WHO...