Lance-Adams syndrome (LAS) is an uncommon neurological disorder characterized by the development of chronic post-hypoxic myoclonus. There are relatively few cases described following successful cardiopulmonary resuscitation. We report a patient who developed LAS 3 months after successful resuscitation. Cerebral imaging studies indicate that brain pathology in LAS patients is not uniform, sugges...

Accurate prediction of neurological outcome in survivors of cardiac arrest may be difficult. We report the case of a 44-year-old survivor of a hypoxic cardiac arrest who repeatedly developed relentless myoclonic jerks on attempted discontinuation of his propofol infusion. These were initially thought to represent myoclonic status epilepticus before the correct diagnosis of Lance-Adams syndrome ...

A patient comatose after acute anoxia developed bilaterally synchronous, periodic myoclonic jerks most prominently in the bilateral upper limbs. Although the myoclonus seemed to occur spontaneously, electrophysiological studies showed that the myoclonic jerks correlated in timing and size with arterial pulses, and was suppressed by massage over the carotid sinus. It is proposed that the present...

To contrast stimulus-sensitive generalized myoclonus with ensuing multifocal localized myoclonus in a patient with post-anoxic coma, we stressed the clinical as well as electroencephalographical differences between his initial generalized and subsequent focal myoclonus. While generalized myoclonus was presumably of extracortical origin and responsive to valproic acid, alternating Jacksonian sei...

Predicting the neurological outcome in survivors of cardiorespiratory arrest is difficult. A distinction has been made between acute and chronic posthypoxic myoclonus, called myoclonic status epilepticus and Lance-Adams syndrome (LAS), respectively, with the acute condition carrying a bad prognosis. Here, we report a case of a 37-year-old female who developed seizures after a successful cardiop...

Myoclonus is a clinical sign characterized by brief, involuntary, jerky contraction or lapse of muscle group muscles, which can be associated with cerebral disorders, epileptic and drugs. Megestrol acetate (MGA) synthetic derivative progestin, has been widely used in practice for increasing appetite patients severe anorexia malignancies. We experienced 68-year-old female patient who myoclonus a...

Case presentation: Female patient, 14 years old, healthy, with a history of ingestion an unknown amount rodenticide. A few hours after, she presented vomiting, diarrhea, bradycardia, myotic pupils and generalized tonic-clonic seizures, evolving two cardiorespiratory arrests. It was performed the first cardiopulmonary resuscitation maneuvers, including sedation intubation; atropinization vasoact...