endotracheal tube (ett) cuff herniation is a rare, and often difficult to diagnose, cause of bronchial obstruction. we present a case of outside cuff herniation of an endotracheal tube that caused pulmonary right lung atelectasis. a 29-year-old man ,a case of car accident with multiple fractures, was admitted to the emergency ward and transferred to the operating room(or) for open reduction and...

BACKGROUND We aimed to investigate the relationship between increased free fatty acid (FFA) level and early postoperative hypoxemia after coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB). METHODS Ninety-eight consecutive patients undergoing CABG were enrolled. Early postoperative hypoxemia was defined as the lowest of the ratio of arterial oxygen tension (PaO2) to insp...

BACKGROUND AND OBJECTIVES Nocturnal hypoxemia is highly prevalent among patients with CKD. Nocturnal hypoxemia contributes to systemic inflammation, oxidative stress, endothelial cell dysfunction, and activation of the renin-angiotensin system, which are common pathologic mechanisms of CKD progression. This study investigated whether nocturnal hypoxemia is independently associated with CKD prog...

BACKGROUND The purpose of this study is to identify the risk factors for postoperative hypoxemia in patients with Stanford A aortic dissection surgery and their relation to clinical outcomes. METHODS Clinical records of 186 patients with postoperative hypoxemia in Stanford A aortic dissection were analyzed retrospectively. The patients were divided into two groups by postoperative oxygen frac...

Anesthetized dogs were studied to characterize the renal hemodynamic response to acute, transient hypoxemia and to determine the role of renal prostaglandins (PGE and PGF) in that response. Acute hypoxemia of 10 minutes duration (mean arterial Po2 32 ± 9 torr) induced a reversible increase in renal blood flow (RBF) (measured by electromagnetic flow probe) and mean arterial pressure (MAP) with a...

Anesthetized dogs were studied to characterize the renal hemodynamic response to acute, transient hypoxemia and to determine the role of renal prostaglandins (PGE and PGF) in that response. Acute hypoxemia of 10 minutes duration (mean arterial Po2 32 ± 9 torr) induced a reversible increase in renal blood flow (RBF) (measured by electromagnetic flow probe) and mean arterial pressure (MAP) with a...

A gender dimorphic immune response has been observed after trauma and severe hemorrhage, a condition believed to be associated with tissue hypoxia. Although studies have shown that hypoxemia per se in males causes a systemic inflammatory response, it is unclear if the inflammatory response to hypoxemia exhibits gender dimorphic characteristics. To study this, male and female C3H/HeN mice in the...

Hypoxemia depresses cell-mediated immune functions in males, whereas proestrous females do not show such a depression. We hypothesized that elevated systemic estradiol levels in proestrous females prevent hypoxemia-induced immune depression. To study this hypothesis, male C3H/HeN mice were pretreated with 17 beta-estradiol (E(2), 40 microg/kg body wt sc) or vehicle for 3 days before induction o...

Long-term oxygen therapy (LTOT) improves prognosis in patients with COPD and chronic severe hypoxemia. The efficacy in moderate hypoxemia (tension of arterial oxygen; on air, 7.4-8.0 kPa) was questioned by a recent large trial. We reviewed the evidence to date (five randomized trials; 1,191 participants, all with COPD). Based on the current evidence, the survival time may be improved in patient...

Anesthetized dogs were studied to characterize the renal hemodynamic response to acute, transient hypoxemia and to determine the role of renal prostaglandins (PGE and PGF) in that response. Acute hypoxemia of 10 minutes duration (mean arterial Po2 32 ± 9 torr) induced a reversible increase in renal blood flow (RBF) (measured by electromagnetic flow probe) and mean arterial pressure (MAP) with a...