OBJECTIVE The aim of our study was to evaluate the relationship between the elevated TSH and fracture risk in postmenopausal women with subclinical hypothyroidism for evaluation of individuals with a high risk for osteoporotic fractures. DESIGN FRAX score calculation (10-year estimated risk for bone fracture) and measurement of bone markers (osteocalcin and beta cross-laps) were performed in ...

Objective: Determination of frequency occurrence subclinical hypothyroidism (SCH) in a local population obese adults Study design: A cross-sectional study Place and Duration: This was conducted at Sindh Government Lyari General Hospital Karachi from March 2022 to March2023 Methodology: The patients aged between 18 years 55 years. All the participants had body mass index (BMI)of more than 29 kg/...

Background: The decision about whether to screen patients for subclinical hypothyroidism (SCH) is clouded by inconsistent evidence of association of dyslipidemia and other risk factors of cardiovascular disease with SCH and also any benefit from early treatment. Objective: To determine whether the known risk factors of cardiovascular disease such as hypertension, increase in fasting blood gluco...

Introduction Hypothyroidism is clinical syndrome that results from decreased secretion of thyroid hormone gland. Primary accounts for 90-95% all cases hypothyroidism. has various cardiovascular manifestations. With aim early prevention and management manifestation in hypothyroidism this study was conducted. Materials Methods A cross sectional observational conducted Department Medicine Bir Hosp...

OBJECTIVE To determine the association, if any, between thyroid-stimulating hormone (TSH) levels and body mass index (BMI) percentiles in children with primary hypothyroidism who are chemically euthyroid and on treatment with levothyroxine. METHODS This retrospective cross-sectional study consisted of a review of medical records from RUSH Medical Center and Stroger Hospital, Chicago, USA of c...

Thyroid disorders are the most common endocrine disorders. In the present study 51 hypothyroid cases and 50 Euthyroid controls were analysed for Thyroid Profile, Lipid Profile, Body Mass Index (BMI) waist circumference, Hip circumference and waist hip ratio. Out of 51 Hypothyroid subjects studied, 5 are having subclinical Hypothyroidism, 20 are having mild Hypothyroidism, 14 Subjects are having...

OBJECTIVE To establish relationship between obesity and hypothyroidism and to analyze the frequency the frequency of primary hypothyroidism in obese patients and frequency of obesity in primary hypothyroidism patients. METHODS We conducted this retrospective, observational study in the Department of Endocrinology and Obesity Clinic, Medwin Hospital, Hyderabad, India in Mar 2008. In the last 1...

OBJECTIVE Subclinical hypothyroidism and isolated hypothyroxinaemia in pregnancy have been associated with an increased risk of gestational diabetes. We aimed to ascertain if these women have a worse metabolic phenotype than euthyroid pregnant women. DESIGN, SUBJECTS AND METHODS We recruited 956 healthy Caucasian women with singleton, non-diabetic pregnancies from routine antenatal clinics. D...

Background: Metabolic syndrome (MS) and hypothyroidism are well known risk factors for atherosclerotic cardiovascu¬lar disease (ASCVD). Insulin resistance is a common pathogenic mechanism in both, and may result in to significant convergence between MS and hypothyroid population. Aims and Objective: The present study was done to evaluate the relation between hypothyroidism in patients with MS. ...

Adipocytes are not only for energy storage, but are also functionally active cells, producing biologically active peptides called adipocytokines. Adipocytokines control nutrition, thermogenesis, immunity, thyroid and reproductive hormones, and neuroendocrine functions. One of the most important new members of this family is apelin. In patients with thyroid dysfunctions, there are usually change...