The abrupt and hysteretic two-step spin crossover in a new triazole-based 2-D Hofmann-type complex shows a record breaking 120 K intermediate plateau (IP) region stabilized by negative cooperative interactions.

Abstract Purpose of Review Compulsive sexual behavior disorder has been recently included in the 11th revision International Classification Diseases (ICD-11), and possible contribution neurochemical hormonal factors have reported. However, relatively little is known concerning neurobiology underlying this disorder. The aim article to review discuss published findings area. Recent Findings Evide...

Introduction: Gonadotropin inhibitory hormone (GnIH) and Agouti-related peptide (AgRP) are orexigenic peptides expressed in the arcuate nucleus (Arc) of the hypothalamus in the ewe. In addition, effects of GnIH and AgRP on the regulation of gonadotropin releasing hormone secretion have been shown in some mammals. The objective of the present study was to investigate the coexpression of GnIH ...

Abstract Spexin (SPX) is a pleiotropic peptide with highly conserved protein sequence from fish to mammals and its biological actions are mediated by GalR2/GalR3 receptors expressed in target tissues. Recently, SPX was found be novel satiety factor models but whether the has similar function still unknown. Using mouse as model for mammalian species, functional role of feeding control mechanisms...

abstract deep seated cavernous angioma (ca) is a very rare entity, those occurring in the hypothalamus are still less common. we present a case of a 52-year-old man who presented with behavior and memory disturbance attacks. he had a ca of the hypothalamus as revealed by magnetic resonance imaging (mri). we will discuss the role and importance of imaging in such scenario and also the differenti...

melanocortin- 4 receptor (mc4r) and agouti- related peptide (agrp) are involved in energy homeostasis in rats. according to mc4r and agrp effects on luteinizing hormone (lh) secretion, they may influence the estrous cycle of rats. therefore, the aim of this study was to investigate the expression of mc4r and agrp mrnas at different stages of estrous cycle in the rat’s hypothalamus. the estrous ...