نتایج جستجو برای: hyposmia

تعداد نتایج: 373  

2004
Mitsuru FURUKAWA

Chronic rhinosinusitis is the most frequent cause of hyposmia. We established a new experimental animal model to investigate pathological findings in the olfactory epithelium and olfactory bulb of rats and describe the possible etiology of hyposmia due to rhinosinusitis. Not only dysfunction of the olfactory epithelium but a central type of hyposmia caused by disorders of the olfactory bulb was...

Journal: :JAMA otolaryngology-- head & neck surgery 2013
Robert I Henkin Loren Schmidt Irina Velicu

IMPORTANCE Olfaction is a complex sensory process that has not been fully studied. Elevated plasma levels of interleukin 6 (IL-6) have been found in patients with several acute and chronic diseases but have not been reported in patients with smell loss (hyposmia). OBJECTIVE To determine IL-6 levels in patients with hyposmia. DESIGN Retrospective study. All measurements were made without ref...

Journal: :The Egyptian Journal of Otolaryngology 2021

Abstract Background Olfaction is a complex process involving different neurological mechanisms with correlation between the chemical structure and quality of odors regarding pleasantness. This study aimed to compare detection pleasant unpleasant in grades hyposmia. A descriptive cross-sectional was conducted preceded by preliminary pilot study, including 20 normal subjects without history The c...

Journal: :Brain : a journal of neurology 2007
K Stiasny-Kolster S-C Clever J C Möller W H Oertel G Mayer

Patients with idiopathic rapid eye movement sleep behaviour disorder (RBD) frequently develop Parkinson's disease and the majority present with hyposmia, which is a potential preclinical non-motor sign of Parkinson's disease. Accordingly, it has been proposed that the clinical symptoms of hyposmia and RBD in combination have to be considered as very early symptoms of Parkinson's disease. Since ...

2018
Noritaka Yoneyama Hirohisa Watanabe Kazuya Kawabata Epifanio Bagarinao Kazuhiro Hara Takashi Tsuboi Yasuhiro Tanaka Reiko Ohdake Kazunori Imai Michihito Masuda Tatsuya Hattori Mizuki Ito Naoki Atsuta Tomohiko Nakamura Masaaki Hirayama Satoshi Maesawa Masahisa Katsuno Gen Sobue

OBJECTIVE Severe hyposmia is a risk factor of dementia in Parkinson's disease (PD), while the underlying functional connectivity (FC) and brain volume alterations in PD patients with severe hyposmia (PD-SH) are unclear. METHODS We examined voxel-based morphometric and resting state functional magnetic resonance imaging findings in 15 cognitively normal PD-SH, 15 cognitively normal patients wi...

2017
Yuanyuan Li Wenyan Kang Linyuan Zhang Liche Zhou Mengyue Niu Jun Liu

Objective: Hyposmia may occur simultaneously with REM sleep behavior disorder (RBD) as a specific phenotype in Parkinson's Diseases (PD), of which the disease progression is fast. In the study, we tried to identify whether the genotypic characteristics could participate in the co-occurrence of hyposmia and RBD in PD patients. Methods: 152 PD patients were recruited from the Department of Neurol...

Journal: :Archives of otolaryngology--head & neck surgery 2004
Daniel V Santos Evan R Reiter Laurence J DiNardo Richard M Costanzo

OBJECTIVE To evaluate the risk of olfactory-related hazardous events in patients with impaired olfactory function. DESIGN Retrospective cohort study. SETTING A university-based clinic for smell and taste disorders. PATIENTS A total of 445 patients who underwent olfactory testing between 1983 and 2001. INTERVENTIONS Patient interview, olfactory testing. MAIN OUTCOME MEASURES (1) Freque...

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